Infertility Clinical Trial
— IntralipidOfficial title:
Does Intralipid Infusion Improve the Implantation Rate in Repeated Implantation Failure: a Randomized Controlled Trial
Verified date | September 2016 |
Source | Cairo University |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Food and Drug Administration |
Study type | Interventional |
Intralipid infusion can improve outcome in women with recurrent Intracytoplasmic sperm injection ( ICSI) failure due to elevated TH1 cytokine response.
Status | Completed |
Enrollment | 200 |
Est. completion date | June 2014 |
Est. primary completion date | September 2013 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 20 Years to 40 Years |
Eligibility |
Inclusion Criteria: - Infertile patients undergoing ICSI cycle with history of repeated implantation failure Exclusion Criteria: 1. Disturbances of normal fat metabolism such as pathologic hyperlipemia 2. Allergic to it; or to eggs, soybean oil, or safflower oil. 3. Severe liver disease, kidney disease, lung disease, anemia, blood clotting disorder. 4. Uterine fibroid, endometrial polyp, endometriosis and hydrosalpinx. |
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Egypt | Kasr Al-ainy hospital | Cairo |
Lead Sponsor | Collaborator |
---|---|
Cairo University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | clinical pregnancy rate | pregancy sac with fetal heart activity | 10 month | No |
Secondary | implantation rate | the number of gestational sacs divided by the number of embryos transferred | 10 month | No |
Secondary | ongoing pregnancy rate | clinical pregnancy continue after 12 weeks gestational age | 14 month | No |
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