Infertility Clinical Trial
Official title:
A New Tool for Automatic Ovarian Follicle Count and it Abilities to Evaluate Ovarian Reserve
The ultrasound unit in Meir Medical Center developed new software to automated ovarian
follicle count on the basis of 3D US. The investigators intent to evaluate this software at
two steps:
- To compared the abilities of the software to physician follicle count.
- To evaluate with the software the antral follicle count, as expression to ovarian
reserve at 3 different time of the month.
The investigators believe that the software measurement of the small follicle can be better
than the common antral follicle count that is use today, and by this accurate evaluation of
the small follicle the investigators can evaluate the ovarian reserve at any time of the
mount, and not only at the early follicular phase that use today.
Antral follicle count (AFC) is one of the methods to evaluate ovarian reserve. But this
method is not that straightforward with a lot of inter and intra observe variation. In
attempt to overcome this problems we going the verified a new software for automated AFC.
At the first step we will compare the human count and the software count of the AFC in 150
exams of ovaries at 3D US.
At the second step we will use the software to evaluate ovarian reserve at 50 women before
fertility treatment. This woman will be questioned about epidemiologic data (age, ethnicity,
medical history) and evaluate at the early follicular phase with blood test for follicle
stimulating hormone, luteinizing hormone , E2, anti-mullerian hormone , Prolactin,
thyroid-stimulating hormone, Testosterone, Progesterone, 17-hydroxyprogesterone,
dehydroepiandrosterone-Sulphate. The evaluation of the AFC by US will be at early follicular
phase, late follicular phase and mid luteal phase
;
Observational Model: Cohort, Time Perspective: Prospective
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