Infertility Clinical Trial
Official title:
Comparison of Micro Dose Gonadotropin-Releasing Hormone (GnRH) Agonist Flare up & Flare Protocol in Poor Responders in Assisted Reproductive Technology (ART) Cycle
Verified date | November 2009 |
Source | Royan Institute |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
About 9 to 24 % of women undergoing in vitro fertilization (IVF) treatment respond poorly to the usual gonadotrophin stimulation protocol applied. Several induction ovulation treatments have been suggested for increasing pregnancy rate. In this study, the investigators will compare the outcome of Microflare protocol and Flare up regimen in poor responders.
Status | Completed |
Enrollment | 200 |
Est. completion date | February 2010 |
Est. primary completion date | January 2010 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 30 Years to 42 Years |
Eligibility |
Inclusion Criteria: Poor responders (Presence of at least two of following items is necessary for inclusion to the study) - History of Cycle Cancellation - History of oocyte number 3 (in previous cycle) - History of Number of antral follicle < 5 in previous cycle - Age=38 - FSH>12 on day 2 or 3 - Ovarian Volume 3 cm3 Exclusion Criteria: - Male factor (azospermi) - Myoma =6cm - One way ovary - Tumor or cyst >13mm - Age >42 |
Country | Name | City | State |
---|---|---|---|
Iran, Islamic Republic of | 1- Endocrinology and Female Infertility Department, Reproductive Medicine Research Centre, Royan Institute, ACECR | Tehran |
Lead Sponsor | Collaborator |
---|---|
Royan Institute |
Iran, Islamic Republic of,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Live birth rate | 12 months | ||
Secondary | Cycle cancellation rates | 12 Months | ||
Secondary | Number of oocytes generated | 12 Months | ||
Secondary | Number of embryos generated | 12 Months | ||
Secondary | Implantation rate | 12 Months | ||
Secondary | Pregnancy rate | 12 months |
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