Infertility Clinical Trial
Official title:
The Use of FSH Receptor Polymorphisms To Improve Pregnancy Rates In In-Vitro Fertilization
This study is being done to identify if certain sequences (patterns) of key genes (called polymorphisms) may predict a response to fertility medications. The investigators will also determine if the individual response to fertility medications affects pregnancy rates in in-vitro fertilization.
Status | Completed |
Enrollment | 75 |
Est. completion date | May 2013 |
Est. primary completion date | March 2013 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 35 Years |
Eligibility |
Inclusion Criteria: 1. 100 women less than 35 years old at time of signing the Informed Consent Form. 2. Day 3 FSH level less than or equal to 10 mIU/ml with an estradiol < 70 pg/ml 3. Day 3 antral follicle count of greater than 10 follicles total. 4. Couples who have male factor infertility, tubal factor infertility, and unexplained infertility. Exclusion Criteria patients who have: 1. Endometriosis 2. Polycystic ovarian syndrome |
Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
United States | University Reproductive Associates | Hasbrouck Heights | New Jersey |
United States | University Reproductive Associates | Hoboken | New Jersey |
Lead Sponsor | Collaborator |
---|---|
University Reproductive Associates | Ferring Pharmaceuticals |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The primary outcome measure is to evaluate the frequency of FSH receptor polymorphisms in our population. | The investigators are looking to quantify how often certain FSH receptor Polymorphisms occur in the population and cetain racial groups. We will be looking at patient's race along with the laboratory results. | 3 years | No |
Secondary | The secondary outcome is to further clarify the variation in response to FSH due to FSH receptor polymorphisms using the protocols largely used in the United States, including our center. | 3 years | No |
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