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Endometrial Markers and Response of Endometriosis Patients to Prolonged GnRH Agonist Prior to IVF — IntegrinIVF  

Infertility Clinical Trial

Official title:
Do Endometrial Implantation Markers Predict in Vitro Fertilization-embryo Transfer Cycle Outcomes in Endometriosis Patients Pretreated With Leuprolide Acetate in Depot Suspension?

Clinical Trial Summary

This prospective randomized trial evaluates whether one can predict which infertile women with endometriosis who are candidates for in vitro fertilization will benefit from prolonged therapy with a GnRH agonist by the determination of the absence of endometrial expression of the integrin, alpha v, beta 3 vitronectin. This is a prospective randomized trial in which all patients will undergo endometrial biopsy prior to initiation of ovarian stimulation for in vitro fertilization and then undergo randomization to a three month course of a depot preparation of the GnRH agonist leuprolide acetate in depot suspension prior to ovarian stimulation or standard therapy. prio

Clinical Trial Description

See summary ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00621179
Study type Interventional
Source Colorado Center for Reproductive Medicine
Contact
Status Completed
Phase Phase 4
Start date March 2003
Completion date January 2010
View Details
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