Infertility Clinical Trial
Official title:
Randomized Controlled Trial Comparing the Long GnRH Agonist Protocol and the Flexible GnRH Antagonist Protocol of Ovarian Stimulation in Normal Responders
The purpose of this study is to compare the efficacy of two controlled ovarian stimulation protocols, the GnRH agonist protocol, widely known as the "long" protocol, and the flexible GnRH antagonist protocol, in terms of pregnancy rates and embryological data, in infertile patients receiving IVF treatment.
The formulation of controlled ovarian stimulation protocols is one of the primary reasons
for the successful development of IVF. The "long" GnRH agonist protocol, also known as the
gold standard, has been widely used with considerable success. More recently, on the other
hand, GnRH antagonist provide a new promising approach for endogenous gonadotrophin
suppression by blocking the GnRH receptor. There is conflicting data in the literature
regarding the relative merits of the two ovarian stimulation protocols.
COMPARISON: Pregnancy rates and embryological data will by assessed in IVF patients treated
with either the "long" GnRH agonist (Arvekap) or the flexible GnRH antagonist (Ganirelix)
protocol.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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