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NCT00411021 Clinical Trial

Endometrial Sampling (Pipelle)in IVF Patients

Infertility Clinical Trial

Official title:
Endometrial Sampling (Pipelle)in IVF Patients

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT00411021
Other study ID # SHEBA-05-3674-MB-CTIL
Secondary ID
Status Recruiting
Phase N/A
First received December 12, 2006
Last updated December 12, 2006

Study information
Verified date December 2006
Source Sheba Medical Center
Contact Micha Baum, MD
Email baumdr@zahav.net.il
Is FDA regulated No
Health authority Israel: Israeli Health Ministry Pharmaceutical Administration
Study type Interventional

Clinical Trial Summary

A prospective cross-over randomized study aimed to test the hypothesis that local injury of the endometrium increases the implantation rate in the successive cycle. Seventy IVF patients will be randomly selected to undergo either endometrial biopsies or minimal cervical scratch on days 8-10 and 21-23 of their cycle, preceding the IVF treatment. If not pregnant, the women will continue for another IVF cycle, preceded by endometrial or cervical scratch complimentary to their procedure in the first cycle. The main major outcomes will include pregnancy rate, implantation rate, endometrial thickness, abortion rate, live births and embryo quality.

Recruitment information / eligibility
Status Recruiting
Enrollment 70
Est. completion date
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 20 Years to 45 Years
Eligibility Inclusion Criteria:

- Women undergoing IVF treatment

- Repeated Implantation failure

Exclusion Criteria:

- PID or suspected PID

- Undiagnosed Irregular Bleeding

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Procedure:
• Pipelle (Endometrial Sampling)

Locations
Country Name City State
Israel IVF Unit, Sheba Medical Center Ramat-Gan

Sponsors (1)
Lead Sponsor Collaborator
Sheba Medical Center

Country where clinical trial is conducted

Israel, 

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