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Infertility clinical trials

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NCT ID: NCT05413629 Completed - Infertility, Female Clinical Trials

The Effect of Web Based Education on the Level of Coping With Infertility Stress and Infertility Self-Efficacy

education
Start date: April 1, 2022
Phase: N/A
Study type: Interventional

In the study, it is aimed to reduce the infertility stress level of women undergoing infertility treatment, to increase the level of coping with infertility stress, to increase infertility self-efficacy, to evaluate the usability of web-based education in the field of infertility, to increase the effectiveness and quality of education by integrating web-based education into the nursing care process, and continuous traceability, to prevention of possible wrong treatment process management in the field of infertility, to prevention of possible loss of cycles and to prevention the material and moral couple from being adversely affected by this process. Method: The study was planned to be carried out between 20.01.2022 and 01.06.2023 with women between the ages of 23-39 who applied to Düzce University Health Practice and Research Center, Infertility Polyclinic. In the research, the Solomon four-group design sample design consisting of two experimental and two control groups will be used. The study planned to consist of a total of 132 patients, 33 patients in each group, taking into account possible data losses. By design, all of the pre-test and post-test measurement tools will be applied to the first experimental and control group, and only the post-test measurement tools will be applied to the second experimental and control group. Randomization will be applied in determining the experimental and control groups. The data will be collected using Personal Information Form (Appendix-1), Infertility Stress Scale (ISS) (Appendix 2), Coping with the Infertility Stress Scale (CISS) (Appendix-3), and Infertility Self-Efficacy Scale - Short Form (ISE-SF) (Appendix 4). Research data will be collected in approximately day 24 to 27 days for each patient from the initiation of Controlled Ovarian Stimulation (COS) treatment to pregnancy determination of patients planned for intrauterine insemination (IUI) treatment. Web-based training is 60 minutes in total, including 4 modules. The web-based training content includes general information about fertility, infertility diagnosis-treatment methods, drugs used in IUI treatment and its application, and issues to be considered after IUI.

NCT ID: NCT05399212 Completed - Clinical trials for Spermatogenesis and Semen Disorders

Composition for Treating Spermatogenesis and Semen Disorders / FPT-20

Start date: October 29, 2020
Phase: N/A
Study type: Interventional

Research to develop a new, natural-derived formulation that eliminates inflammatory tissue and regenerates new tissue of the lobules, epithelium of the tubules, and connective tissue surrounding the seminiferous tubules in the testes. It restores Leydig cells and Sertoli cells' function (because the inflamed testicles were unable to perform spermatogenesis).

NCT ID: NCT05397314 Completed - Infertility, Male Clinical Trials

DNA Fragmentation - Effect on Pregnancy Rate

Start date: January 1, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether Punalpin, an antioxidant, has a positive impact on DNA fragmentation in spermatozoa in male fertility patients with increased amount of DNA fragmentation in their spermatozoa. Secondary purpose is to investigate whether there is any positive effect on the subsequent pregnancy rates from the fertility treatment.

NCT ID: NCT05393011 Completed - Infertility Clinical Trials

Relationship Between Some Vitamins and Antioxidants With in Vitro Fertilization Outcomes

Start date: August 20, 2017
Phase:
Study type: Observational

observation of females condition will getting pregnant by undergoing assisted reproductive technologies, the most important of which is the in vitro fertilization (IVF), where blood and follicular fluid samples are collected from them at the same stage of in vitro fertilization, and then monitor the IVF outcomes until pregnancy occurs or not, based on blood tests. The levels of interested markers in blood and follicular fluid samples of the study individuals are assayed in order to compare these levels with the egg criteria such as egg number and maturation rate and finally compare the results with occurrence or absence of pregnancy.

NCT ID: NCT05368194 Completed - Nutrition, Healthy Clinical Trials

Food Intake and Epigenetic Alteration in the Spermatozoa of Singletons and Twins

FEASST
Start date: October 20, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to elucidate the role of acute dietary intake in male populations, and its impact on spermatozoa quality, integrity, content and epigenetic programming.

NCT ID: NCT05364528 Completed - IVF Clinical Trials

Pregnancy Rate in Direct Versus Afterload Technique of Embryo Transfer

Start date: January 1, 2016
Phase:
Study type: Observational

The primary outcome of the study is to determine if a difference in terms of pregnancy rate exists between direct and afterload embryo transfer (ET) techniques. The secondary end points include the evaluation of the difficult transfer rates.

NCT ID: NCT05358392 Completed - Infertility Clinical Trials

"Effect of Emotional Freedom Technique "

(EFT)
Start date: May 1, 2022
Phase: N/A
Study type: Interventional

This study will be conducted to investigate the effect of Emotional Freedom Technique (EFT) Application on infertility stress in women undergoing infertility treatment.

NCT ID: NCT05320289 Completed - Clinical trials for Polycystic Ovary Syndrome

Feasibility Study of the AblaCare System in Transvaginal Ablation of Ovarian Tissue Under ULTRAsound Visualization in Women With Infertility Due to Polycystic Ovary Syndrome

ULTRA-US
Start date: May 12, 2022
Phase: N/A
Study type: Interventional

The objective of the study is to provide preliminary evidence for the safety and effectiveness of the AblaCare System in transvaginal ablation of ovarian tissue under ultrasound visualization in women with infertility due to polycystic ovary syndrome (PCOS) who have not responded to first-line ovulation induction treatment or are contraindicated for or decline such treatment.

NCT ID: NCT05310617 Completed - Infertility Clinical Trials

Parental Project and Premature Ovarian Insufficiency

ParentIOP
Start date: June 20, 2022
Phase:
Study type: Observational

One of the main repercussions of POI is infertility. When the diagnosis of POI is announced, the question of fertility is addressed and the patient is often directed towards egg donation or adoption when she has a parental project. However, there are cases of spontaneous pregnancies after diagnosis. This study was conducted to determine the proportion of patients with POI who were able to realize a parental project after diagnosis in the long term and by what means.

NCT ID: NCT05286554 Completed - Female Infertility Clinical Trials

Addition of Gonadotropin Releasing Hormone Agonist to Luteal Phase Support

Start date: March 17, 2022
Phase: Phase 4
Study type: Interventional

Hormonal milieu during implantation is crucial to embryo-endometrium interaction and to the viability of the conceptus. Alterations in the peri-implantation environment are considered to impair perinatal outcomes in intracytoplasmic sperm injection (ICSI) therapy. GnRH-a is a new and promising modality for LPS. Regimens for using GnRH-a in LPS, including single mid-luteal bolus or the addition of a GnRH-a to progesterone supplementation, have been recently suggested. The aim of this study is to evaluate the impact of addition of mid-luteal single-dose or multiple-dose GnRH agonist to the routine luteal phase support in patients undergoing ICSI cycles using GnRH antagonist protocol.