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Infertility clinical trials

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NCT ID: NCT02304107 Completed - Infertility Clinical Trials

Comparison Between Letrozole and Urinary Purified FSH in Women With Clomiphene Citrate Resistant Polycystic Ovarian Syndrome.

FSH
Start date: May 2013
Phase: Phase 3
Study type: Interventional

210 women with clomiphene resistant PCOS will be randomly divided into 3 equal groups using computer generated random numbers. Group 1 will receive FSH, group 2 will have Letrozole and group 3 will act as the control group with no intervention.

NCT ID: NCT02302781 Completed - Subfertility Clinical Trials

Why Subfertile Couples Drop Out

DOT
Start date: April 2015
Phase:
Study type: Observational [Patient Registry]

Dropout rates for fertility treatments are high. This study will examine the rate of patients that drop out during any type of subfertility work up or treatment. Furthermore, we will determine what reasons for discontinuation are and we will identify the demographic characteristics of the couples and the prognostic factors for drop out during assessment or treatment at a Fertility Centre in the Isala (Zwolle), Erasmus University Centre (Rotterdam), Elisabeth Twee Steden Hospital (Tilburg), Reinier de Graaf Group (Voorburg), St Antonius Hospital (Nieuwegein), Maxima Medical Centre (Veldhoven) and Noordwest Hospital Group (Den Helder/Alkmaar) in The Netherlands.

NCT ID: NCT02302638 Completed - Infertility Clinical Trials

Embryo Development Using Two Commercial Single-step Media

Start date: November 2014
Phase: N/A
Study type: Interventional

This prospective study with sibling oocytes will evaluate the efficiency of two commercial single-step media, namely Sage 1-step and Continuous Single Culture Medium (CSCM), in terms of embryo utilization rates, blastocyst formation rates, embryo quality and pregnancy rates. Embryos will be cultured continuously for up to 6 days under identical conditions.

NCT ID: NCT02294773 Completed - Infertility Clinical Trials

Study Evaluating the Timing of Intrauterine Insemination in Relation to Positive Home Ovulation Prediction Kit

Start date: October 2013
Phase: N/A
Study type: Interventional

The aim of this study is to assess the impact of the timing of intrauterine insemination (IUI) in relation to the natural surge of luteinizing hormone (LH), as detected by home ovulation predictor kits, on pregnancy rates per treatment cycle. The study will take place at the offices of Midwest Fertility Specialists and include patients who have been independently recommended by their primary physician to undergo ovulation induction with clomiphene citrate (CC) or letrozole and IUI as therapy for infertility.

NCT ID: NCT02293668 Completed - Infertility Clinical Trials

Outcome of Three Controlled Ovarian Hyperstimulation Protocols in Poor Responding Infertility Patients

Start date: November 2014
Phase: N/A
Study type: Interventional

There are different controlled ovarian hyperstimulation protocols utilized in infertility patients. In this study, our aim is to specifically compare three protocols in poor responding infertility patients.

NCT ID: NCT02290002 Completed - Infertility Clinical Trials

Calcium Dobesilate Versus Coasting for Prevention of Ovarian Hyperstimulation Syndrome

Start date: June 2014
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to compare the effect of oral Calcium Dobesilate versus costing in the prevention of ovarian hyperstimulation syndrome (OHSS) in high-risk women underwent intracytoplasmic sperm injection (ICSI).

NCT ID: NCT02288143 Completed - Infertility Clinical Trials

COmbining Oral Letrozole and Clomiphene for Ovarian Stimulation

COOL-COS
Start date: January 2015
Phase: Phase 4
Study type: Interventional

This is a pilot study evaluating the effect of a simplified low-cost (friendly) controlled ovarian stimulation using clomiphene citrate, letrozole, and low-dose hMG on the number of oocytes retrieved.

NCT ID: NCT02273791 Completed - Infertility Clinical Trials

HRT Versus MOS for Endometrial Preparation Prior to FET in PCOS Patients

Start date: December 2013
Phase:
Study type: Observational

Evaluation of endometrial preparation using either hormonal therapy or ovarian stimulation prior to frozen-thawed embryo transfer (FET) in patients with polycystic ovarian syndrome (PCOS)

NCT ID: NCT02272439 Completed - Male Infertility Clinical Trials

Endocrine Disrupting Chemicals: Potential Effects on Male and Female Reproductive Health in Saskatchewan

Start date: March 2012
Phase: N/A
Study type: Observational [Patient Registry]

The overall objective of this study is to determine whether serum BPA and/or phthalate concentrations differ in fertile versus infertile men and women in Saskatchewan. The investigators will test the following hypothesis: 1. Serum BPA and/or phthalate concentrations will be greater in women with unexplained infertility or PCOS compared to a control group 2. Serum BPA and/or phthalate concentrations will be greater in men with male factor infertility compared to a control group

NCT ID: NCT02271360 Completed - Infertility Clinical Trials

Calcium Dobesilate Versus Cabergoline for Prevention of Ovarian Hyperstimulation Syndrome

Start date: April 2014
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to compare the effect of oral Calcium Dobesilate to oral Cabergoline in the prevention of ovarian hyperstimulation syndrome (OHSS) in high-risk women underwent intracytoplasmic sperm injection (ICSI).