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Infertility clinical trials

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NCT ID: NCT03185715 Completed - Infertility, Female Clinical Trials

Oocyte Recipient's Decision in the Number of Embryos to be Transferred

Start date: October 2014
Phase: N/A
Study type: Interventional

Multiple pregnancies are considered an ART complication. The only effective way to reduce its incidence is to transfer a single embryo. Nonetheless, there is some reluctance among the patients to accept this strategy. In IVF/ICSI programs, it has been demonstrated that, after receiving the information about the similar cumulative live birth rate after single embryo transfer (SET) and double embryo transfer (DET) and the obstetric and perinatal risks of multiple pregnancy, a significant number of patients opt for SET. Up to date, no comparable studies have been published in oocyte recipients. The aim of this study is to evaluate if the information given to the patients influence their preference on the number of embryos to be transferred. It also seeks to identify factors which determine the initial preference and factors which can explain a hypothetic change in this preference.

NCT ID: NCT03181919 Completed - Clinical trials for Infertility Poly Cystic Ovary

Letrozole Step-up Protocol for Ovulation Induction in Infertile Women With PCOS

Start date: January 1, 2016
Phase: N/A
Study type: Interventional

the aim of the study is to compare between the step-up and conventional protocols in ovulation induction in infertile women with PCOS

NCT ID: NCT03181243 Completed - Male Infertility Clinical Trials

The Acceptance, Safety, and Efficacy of MadaJet Versus Needle Injection for Sperm Retrieval in Patients With Azoospermia

Start date: July 15, 2017
Phase: N/A
Study type: Interventional

To compare the acceptance, safety, and efficacy of needle-free jet anaesthetic technique (MadaJet) versus needle injection for sperm retrieval in patients with azoospermia.

NCT ID: NCT03178695 Completed - Infertility Clinical Trials

Inovium Ovarian Rejuvenation Trials

Start date: June 1, 2017
Phase: Phase 1
Study type: Interventional

The Inovium Ovarian Rejuvenation Treatment is a PRP-based autologous treatment used in combination with a stimulated IVF sequence and Pre-Implantation Genetic Screening to treat infertility in women experiencing menopause, perimenopause, and premature ovarian failure.

NCT ID: NCT03177538 Completed - Infertility, Female Clinical Trials

Corifollitropin Alfa Combined With Menotropin Versus Follitropin and Lutropin Alfa in Expected Suboptimal Responders

TEMPER
Start date: September 4, 2017
Phase: Phase 4
Study type: Interventional

In an opened randomized study of women undergoing in vitro fertilization with expected suboptimal response to controlled ovarian stimulation (Poseidon Group 2b) investigators will examine clinical efficacy and safety of two stimulation protocols: Corifollitropin alfa (Elonva) in combination with menotropin (Merional) versus Follitropin alfa and lutropin alfa (Pergoveris).

NCT ID: NCT03174691 Completed - Infertility Clinical Trials

Early Luteal Progesterone Profile in IVF Patients Triggered With hCG

Start date: June 7, 2017
Phase: N/A
Study type: Interventional

Until now very little information exists regarding the early luteal serum progesterone profile after Human chorionic gonadotropin (hCG) trigger. This pilot study will help characterize the serum progesterone, 17-hydroxyprogesterone profiles in IVF patients and correlate progesterone, 17-Hydroxyprogesterone levels to ovarian follicles obtained after stimulation with exogenous gonadotropins.

NCT ID: NCT03173404 Completed - Sterility Clinical Trials

Benefits of Hysteroscopy Prior to Performing a Cycle of in Vitro Fertilization/Intracytoplasmic Sperm Injection

Start date: July 1, 2014
Phase: N/A
Study type: Interventional

This is a prospective randomized open-label trial. Women scheduled for their first or second in-vitro fertilization/intracytoplasmatic Sperm Injection (IVF/ICSI) cycle and with no abnormality detected in transvaginal ultrasound examination, were randomized to two groups. In the first group (group I) 31 patients underwent hysteroscopy examination before IVF cycle while in the second group (group II) 37 patients underwent direct cycle without previous hysteroscopy

NCT ID: NCT03169166 Completed - Infertility Clinical Trials

The Use of GnRH Agonist Trigger for Final Follicle Maturation in Women Undergoing Assisted Reproductive Technologies

Start date: March 1, 2017
Phase: Phase 4
Study type: Interventional

This is a prospective comparative randomized controlled trial investigating the effect of two GnRH agonist trigger protocols on the ongoing pregnancy rate in hyper-responder women undergoing assisted reproductive technology.

NCT ID: NCT03166657 Completed - Infertility, Female Clinical Trials

Office Hysteroscopy in Secondary Infertility After Cesarean Section

Start date: March 1, 2018
Phase:
Study type: Observational

All women with history of secondary infertility after caesarean section will be subjected to office hysteroscopy according to Royal college of obstetrics and gynecology guidelines to diagnose any subtle uterine abnormalities not detected by conventional means. Hysteroscopic examination will be done during the proliferation phase of the menstrual cycle. The hysteroscopic evaluation will include assessment of the cervical canal, intrauterine lesions, the endometrium and the uterotubal junction. . If hysteroscopy reveal a lesion, its type, size, location will be recorded. Transvaginal ultrasound will be done after the procedure to detect fluid in the douglas pouch to confirm patent tubes. Asses the uterine scar in details.

NCT ID: NCT03166189 Completed - Infertility, Female Clinical Trials

Autologous Bone Marrow-derived Mesenchymal Stem Cells for Atrophic Endometrium in Patients With Repeated IVF Failures

Start date: December 20, 2017
Phase: Phase 2
Study type: Interventional

Investigators will examine safety and efficiency of the cell product of autologous bone marrow-derived mesenchymal stem cells (MSC) for patients with repeated IVF failures and hypoplastic or/and fibrosis process of endometrium