Infertility, Male Clinical Trial
Official title:
Assessment of Seminal Levels of Cystatin C and Endoglin in Infertile Men With Varicocele
Varicocele is a major contributor in male infertility. The improvement of sperm parameters after varicocelectomy supports this contribution. The pathophysiological mechanisms of varicocele-induced male infertility are still under investigation. Cystatin C (Cys C) and endoglin are secreted glycoproteins that recently linked to several cellular changes common in varicocele like apoptosis and autophagy.
Subinguinal varicocelectomy under general anesthesia and complete aseptic condition was done to infertile men with varicocele ;
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