Pathogen Detection in Infectious Uveitis

Infectious Iridocyclitis Clinical Trial

Official title:

Pathogen Detection in Infectious Uveitis in China

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04521673
• Other study ID #: XH-20-014
• Status: Recruiting
• Start date: October 1, 2020
• Est. completion date: September 30, 2022

Study information

• Verified date: August 2020
• Source: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
• Contact: Ping Fei, MD,PhD
• Phone: 86-13636342098
• Email: shirleypingfei[@]126.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Infectious uveitis is a very important blinding disease. Some people who have been diagnosed with idiopathic uveitis may also have the activity of pathogens in the eye. However, due to the limitation of the amount of ocular samples, it is difficult to make a rapid and effective diagnosis of infection.Current study is to explore the infective cause of uveitis in China by using a broad diagnostic approach of detection.

Description:

Infectious uveitis is a very important blinding disease. Some people who have been diagnosed with idiopathic uveitis may also have the activity of pathogens in the eye. However, due to the limitation of the amount of ocular samples, it is difficult to make a rapid and effective diagnosis of infection.

The study is to explore the infective cause of uveitis in China by using a broad diagnostic approach of detection, including multiple molecular bio-techniques. We also plan to explore the distribution of pathogens in infectious uveitis.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: September 30, 2022
• Est. primary completion date: September 30, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Patient at a referal hospital eye clinic with clinically suspected infectious uveitis

Exclusion Criteria:

• Patients not eligible for the Inclusion Criteria

• Confirmed auto-immune uveitis

Related Conditions & MeSH terms

• Communicable Diseases
• Infection
• Infectious Iridocyclitis
• Infectious Panuveitis
• Iridocyclitis
• Panuveitis
• Uveitis

Locations

Country	Name	City	State
China	Xinhua Hospital	Shanghai

Sponsors (1)

Lead Sponsor	Collaborator
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Prevalence and distribution of intraocular infections in the study group	Prevalence and distribution of intraocular infections in the study group	Oct 2020 to Sep 2022
Secondary	The sensitivity and specificity of multiple molecular diagnostic methods for detection of bacteria or virus fungi in the study group	The sensitivity and specificity of multiple molecular diagnostic methods for detection of bacteria or virus fungi in the study group	Oct 2020 to Sep 2022