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Immune Response to HPV Vaccine Among HIV-1-infected Subjects in Brazil — HPV  

Infection Clinical Trial

Official title:
Immune Response to HPV Vaccine Among HIV-1-infected Subjects in Brazil

Clinical Trial Summary

Besides the specific response to vaccine antigens, the investigators will analyze the anti-HPV immune response in HIV-1-infected men in different strata of immune deficiency. The hypothesis will be tested by stratification by T CD4 + lymphocytes in an attempt to assess the range of the count with the highest possibility of vaccine response. Thus, knowledge of vaccine response in HIV-infected patients, indicate which patients would have greater potential for vaccine response in vivo.

Clinical Trial Description

The study will be divided into three groups. Patients with HIV-1 infection will be subdivided into groups according to T CD4 + lymphocytes at the time of vaccination: Over 500 CD4 T cells count and bellow 500 CD4 T cells count. A healthy control group will be also studied. ;

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02236234
Study type Interventional
Source University of Sao Paulo
Contact
Status Completed
Phase Phase 4
Start date January 2012
Completion date January 2014
View Details
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