Herpes Simplex Type 2 Co-infection in Veterans With Chronic Hepatitis C

Status Active, not recruiting

Clinical Trial Summary

This trial is to determine the safety of valacyclovir in persons with chronic hepatitis C and herpes simplex type 2 infection. Participants will be randomized to valacyclovir or matching placebo. After receiving the initial therapy for eight weeks, the participants will cross over to the alternate therapy for an additional eight weeks. Each treatment period will be separated by a two-week period of daily placebo. The hypothesis is that treatment with valacyclovir will result in a significant reduction in serum levels of hepatitis C virus ribonucleic acid.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01037621
Study type	Interventional
Source	G.V. (Sonny) Montgomery VA Medical Center
Contact
Status	Active, not recruiting
Phase	Phase 1
Start date	April 2010
Completion date	February 2012

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