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Infection clinical trials

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NCT ID: NCT04503642 Completed - Morality Clinical Trials

Changing the Surgical Team for Wound Closure and Surgical Site Infection

Start date: March 1, 2018
Phase:
Study type: Observational

Surgical site infection is a frequent complication after abdominal surgery. The wound closure is done at the end of the procedure when the attention of the entire team may be affected because of tiredness and reduced attention of the surgical team. With this study, the investigators aim to test if an exchange of the surgical team by a specialised wound closure team may reduce the impact of surgical site infection.

NCT ID: NCT04501835 Completed - Clinical trials for Cardiac Implantable Electronic Device Infections

Assessment of Diagnostic and Therapeutic Practices for Cardiac Implantable Electronic Devices Suspected Infections in Nancy University Hospital

Start date: July 31, 2019
Phase:
Study type: Observational

The frequency of cardiac implantable electronic devices (CIED) is constantly increasing. Devices infections are one of the most serious complications in terms of morbidity and mortality. Although the frequency of cardiac implantable devices infections is difficult to derminate due to divergent definitions, cohort studies report a trend of increasing. The infection can be localized at the pocket of the implantation, at intravascular or intra-cardiac portion of leads. Infectious endocarditis defined by involvement of the intra-cardiac portion of leads is the most serious form. The diagnosis is based on clinical, biological and multimodal imagery data. Early diagnosis and specific management are necessary to reduce mortality and morbidity. Since the last European recommendations on infectious endocarditis in 2015, the HeartRythm Society of patient described an algorithm to treat CIED infections and extraction indications. However, in practice, management of CEID infections remains center-dependent and data from robust international studies are missing. The main objective of our study is to evaluate the management of CEID suspected infections and the prognosis at 1 year in terms of survival according to the methods of treatment at the Nancy University Hospital and to compare the treatment with the latest recommendations in force

NCT ID: NCT04497753 Completed - Clinical trials for Respiratory Infectious Diseases

An Epidemiological Investigation on Correct Wearing of Mask by Hood Test

Start date: June 19, 2020
Phase:
Study type: Observational

The purpose of this study was to explore the relationship between the transmission of respiratory diseases and the correct wearing of masks, as well as the factors affecting the correct wearing of masks. The research is beneficial to the prevention of respiratory diseases and moves the barrier of prevention and control forward. It is of great significance to COVID-19 's practical prevention and control.

NCT ID: NCT04497675 Completed - Clinical trials for Respiratory Infectious Diseases

An Epidemiological Investigation on Correct Wearing of Mask by Direct Spray Test

Start date: June 19, 2020
Phase:
Study type: Observational

The purpose of this study was to explore the relationship between the transmission of respiratory diseases and the correct wearing of masks, as well as the factors affecting the correct wearing of masks. The research is beneficial to the prevention of respiratory diseases and moves the barrier of prevention and control forward. It is of great significance to COVID-19 's practical prevention and control.

NCT ID: NCT04495764 Completed - Clinical trials for SARS-CoV-2 Infection

Registry of Sustained Immunity to COVID-19 Among ESKD Patients

RePAiR
Start date: July 20, 2020
Phase:
Study type: Observational

This is a multi-center, prospective registry study of subjects undergoing hemodialysis for treatment of end-stage renal disease in a DaVita center. The objective of this study is to understand whether and to what degree anti-SARS-CoV-2 antibodies mitigate the risk of subsequent SARS-CoV-2 infection and COVID disease within the ESKD population.

NCT ID: NCT04492826 Completed - Otolaryngology Clinical Trials

Postoperative Surgical Site Infection afterENT Bone Flap Surgery

SSI-flap
Start date: September 2012
Phase:
Study type: Observational

In 2017, the French Society in anesthesia and reanimation published new recommendations on intraoperative antibiotic prophylaxis. Now, no more than 48 hours of antibiotic prophylaxis applies to any otolaryngology surgery, regardless of patient's medical history or type of flap used to rebuild. This has resulted in an alignment of our local protocol in Croix-Rousse hospital. However, after few years, our local impressions are that bone flap surgeries are very likely to provide surgical site infections (osteo-articular or non-osteo-articular infections). The prejudice of these postoperative site infections is significant, with serious consequences,. of both functional and aesthetic sides. We wanted to objectify this impression by retrospectively analyzing the data relating to patients operated on for bone flapsurgeries. Knowing the operation site infection rate after surgery for otolaryngology bone flap surgery will allow us to objectively understand the infectious risk of these surgeries, in particular the risk of osteoarticular infection. Identifying operation site infection factors will allow us to better target and prevent them. The goal is to find out if the antibiotic prophylaxis currently recommended is sufficient and effective for this type of surgery.

NCT ID: NCT04491214 Completed - Covid19 Clinical Trials

Post ICU Follow up in Patients With Severe SARS-CoV-2 Infection (Covid-19)

Start date: July 24, 2020
Phase:
Study type: Observational

Patients affected by new coronavirus infectious disease (COVID) were mostly hospitalized in ICU. This infection seems to cause widespread organ injury (i.e acute renal injury, neurological disorders, pulmonary embolism,…). It is therefore necessary to provide a framework for the follow up of patients. Moreover SARS-CoV-2 infection consequences remain unknow at this time. Study hypothesis is that COVID alters determining factors (physical or psychological) of quality of life after ICU hospitalisation. The aim of the study is to assess quality of life 3 months after ICU hospitalization. Secondary purposes of the study are 1) assessment of quality of life 6 months and the evolution between the third and the sixth months after ICU hospitalization 2) description patients care after 3 and 6 months ICU left and their clinical status 3) convening and providing a "platform" within several physicians (neurologist, biologist, pneumologist…) will be able to follow up patients and perform complementary investigations according to patients injuries.

NCT ID: NCT04489797 Completed - Infectious Disease Clinical Trials

A Study to Evaluate Effects of Proton-pump Inhibitor on Acalabrutinib Capsule When Administered Orally With COCA-COLA in Healthy Participants

Start date: July 20, 2020
Phase: Phase 1
Study type: Interventional

This study is being conducted to support the clinical development of acalabrutinib in participants who need treatment with proton pump inhibitors while taking acalabrutinib.

NCT ID: NCT04487119 Completed - Covid19 Clinical Trials

Hematology and Clinical Picture in Pediatric COVID-19 Infection

Start date: August 12, 2020
Phase:
Study type: Observational

This study is to discuss the different clinical presentations, hematological and laboratory abnormalities in pediatric COVID-19 infection.

NCT ID: NCT04483518 Completed - Clinical trials for Observe and Describe the Prevalence of Hepatitis D Infection Among HBsAg Positive People

Epidemiological Survey of Hepatitis D Virus Infection in China

Start date: June 3, 2019
Phase:
Study type: Observational

This cross-sectional study will screen out hepatitis D virus-infected patients in HBsAg-positive people. Observe and describe the prevalence of hepatitis D infection among HBsAg positive people. The provinces of China are divided into 5 geographical areas (North, South, East, West and Central) to recruit patients according to the population density of each area. After statistical calculation, the total number of population needed is 3808.