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Infarction clinical trials

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NCT ID: NCT04153591 Completed - Clinical trials for Acute Myocardial Infarction

Efficacy and Safety of Direct Oral Anticoagulants for the Treatment of Mural Thrombus

Start date: November 5, 2019
Phase:
Study type: Observational

To describe the prescribing patterns at Methodist Dallas Medical Center (MDMC) for the treatment of newly diagnosed mural thrombus and to determine the efficacy and safety of DOACs apixaban, dabigatran, and rivaroxaban in comparison to warfarin. With limited treatment guideline consensus, minimal evidence to support the use of DOACs for Left Atrial Appendage (LAA) thrombus and Left Ventricular Thrombus (LVT), and a lack of evidence for the use of DOACs in aortic thrombus, further research is warranted to determine the role of DOACs in the treatment of various mural thrombi in comparison to warfarin.

NCT ID: NCT04153006 Completed - Clinical trials for Myocardial Infarction

Comparison of Fingerstick Versus Venous Sample for Troponin I.

Start date: September 3, 2019
Phase:
Study type: Observational

This study is a prospective, observational, cohort study aiming to compare point-of-care high-sensitive troponin I testing from different sample types with central laboratory (CL) HS cTnI plasma samples. A registry of all included patients and their troponin results (POC, CL and HS cTnT) will be made to compare these testing methods.

NCT ID: NCT04151628 Completed - Clinical trials for Coronary Artery Disease

Disrupt CAD IV With the Shockwave Coronary IVL System

Start date: November 6, 2019
Phase: N/A
Study type: Interventional

The study design is a prospective, multicenter, single-arm study to evaluate the safety and effectiveness of the Shockwave Medical Coronary Intravascular Lithotripsy (IVL) System in de novo, calcified, stenotic coronary arteries prior to stenting.

NCT ID: NCT04138641 Completed - Clinical trials for Coronary Artery Disease

Dutch Cangrelor Registry

Start date: December 17, 2019
Phase:
Study type: Observational [Patient Registry]

Cangrelor is a fast and directly acting platelet aggregation inhibitor. It is potentially indicated for several types of patients who are undergoing PCI. A nationwide cangrelor registry has up until now not been performed and with the introduction of cangrelor in the Netherlands its efficacy and safety will be determined.

NCT ID: NCT04131816 Completed - Clinical trials for Myocardial Infarction

HeartHome: A Nurse-Driven, Home-Based Cardiac Rehabilitation Program

Start date: November 10, 2019
Phase: N/A
Study type: Interventional

The purpose of this implementation trial is to execute a nurse-led, home-based cardiac rehabilitation (HBCR) program, evaluate the program's impact on patient outcomes over 6 months; and compare outcomes of HeartHome (HH) participants to a group of participants in traditional cardiac rehabilitation (CR).

NCT ID: NCT04125992 Completed - Clinical trials for Coronary Artery Disease

Distal vs. Forearm Radial Artery Access

DRAvsFRA
Start date: December 1, 2019
Phase: N/A
Study type: Interventional

The Distal Radial Access (DRA) to the coronaries has emerged recently. It's done via the distal radial artery in the radial fossa, which is known as the snuff-box. The rationale of conducting this research is to assess this new access advantages and disadvantages, in comparison with the standard conventional forearm radial access and examine if it's worthy to be a future alternative method for coronary angiography. It aims to randomly compare between the new distal radial access via the snuffbox and the conventional forearm radial access for percutaneous coronary angiography and angioplasty procedures. The objectives of comparing both procedures are to analyze the frequency of complications in terms of occlusion, arterial spasm, hematoma, and to weigh accesses effectiveness in terms of time and attempts to puncture, crossover rate, procedure duration, hemostasis time, and convenience of the patients and operators. Candidates for coronary angiography are being randomized into the interventional group to undergo the angiography through the distal radial artery as the access site, or the control group accessing through the radial artery in the forearm. Procedural and post procedural outcomes and complications are being reported while patients are in hospital. All patients undergo doppler ultrasonography within 24 hours after the procedure.

NCT ID: NCT04096079 Completed - Clinical trials for Out-Of-Hospital Cardiac Arrest

Post-ROSC Electrocardiogram After Cardiac arrEst

PEACE
Start date: January 1, 2015
Phase:
Study type: Observational

PEACE study retrospectively evaluate patients who suffered an out-hospital cardiac arrest (OHCA) and who underwent a coronary angiography, enrolled in the registry of the Province of Pavia (Italy), Ticino Region (Switzerland), Wien region (Austria) and Nicosia area (Cyprus) to comprehend the best timing for post-ROSC ECG acquisition in order to reduce the number of false positive and to select the best candidates for emergency coronary angiography.

NCT ID: NCT04077294 Completed - Myocardial Injury Clinical Trials

Preoperative BNP: Epidemiological Patterns, Management Strategies and Cost Analysis of Care

Start date: May 21, 2019
Phase:
Study type: Observational

Recently, the use of preoperative BNP as a preoperative risk stratifcation tool was added to the Canadian Cardiovascular Society (CCS) guidelines (4) on perioperative cardiac risk assessment and management for patients who undergo noncardiac surgery, based on the prognostic value of preoperative BNP in indentifiy patients at significant risk of 30-day mortality, nonfatal myocardial infarction, or myocardial injury after noncardiac surgery (MINS). While the value of screening for high risk patients through the use of preoperative BNP been demonstrated, the management of postoperative ischemia is less clear. Therefore, this study aims to: 1. Evaluation of the use of BNP as a preoperative screening biomarker; how often is it ordered in Anesthesia Preadmission Clinic and what is the incidence of a positive result (BNP ≥ 92 ng/L) 2. Determine the incidence of myocardial injury after non-cardiac surgery (MINS) at 30 days and myocardial infarction at 1 year at a tertiary care center when BNP is used as a screening tool 3. Record patterns of management of patients with MINS 4. Determine the cost associated with the different patterns of management of MINS 5. Comparison with a cohort group who qualified for BNP screening according to CCS guidelines but did not have it measured. The investigators will attempt to evaluate the cohort group for MINS at 30 days and myocardial infarction at 1 year.

NCT ID: NCT04063176 Completed - Clinical trials for Myocardial Infarction

Prospective Outpatient Registry of Myocardial Infarction Patients

PROFILE-MI
Start date: March 1, 2014
Phase:
Study type: Observational [Patient Registry]

The investigators enrolled 160 patients who visited Moscow state outpatient clinic №9 (and its two branches) within six months after acute myocardial infarction. The enrollment lasted from 01.03.2014 to 01.07.2015. The observation period is five years. During the first year after enrollment in the study, patients had follow-up visits every two months, from second-year every six months. Analysis of the prescribed therapy and its changes was carried out by the cardiologist in the clinic for the entire observation period, taking into account the concomitant diseases /indications/contraindications. Endpoints (the death, repeated cardiovascular complications (AMI, stroke), emergency hospitalization due to worsening of the main cardiovascular disease, the appearance of clinically significant cardiac arrhythmias, invasive interventions) were defined during out-patient visits and telephone contact

NCT ID: NCT04057404 Completed - Clinical trials for ST Elevated Myocardial Infarction

Smartphone Twelve Lead Electrocardiogram Utility In ST Elevation Myocardial Infarction

ST LEUIS
Start date: September 2015
Phase:
Study type: Observational

The primary objective is to determine if the Smartphone electrocardiogram (ECG) is an acceptable replacement for a standard ECG in the identification of ST elevation myocardial infarction (STEMI).