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Infant clinical trials

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NCT ID: NCT01162798 Completed - Growth Clinical Trials

Preterm Infant Growth

Start date: September 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to assess growth of preterm infants fed a test formula compared to a standard formula up to the first 4 months of corrected gestational age.

NCT ID: NCT01090726 Completed - Intubation Clinical Trials

Intubation With Storz Videolaryngoscope® Versus Airtraq® - in an Infant Population

Start date: March 2010
Phase: N/A
Study type: Interventional

The purpose of the pilot study is to compare new laryngoscopes for infants by assessing the equipment best suited to assist the intubation, with the best overview, shortest time to intubation and use these numbers to make a sample size calculation for the full protocol. The investigators hypothesis is that the Storz videolaryngoscope® has a better success rate than infants (<2 years). The patients will be optimally anaesthetized with neuromuscular blockade for the intubation. All patient will be evaluated with af Macintosh blade laryngoscope, with an Airtraq® or a Storz videolaryngoscope®, and finally intubated with the other one of the later, which the patient was randomized to.

NCT ID: NCT00948051 Completed - Infant Clinical Trials

Effects of follow-on Formula Enriched on Short-chain Fructooligosaccharides (scFOS) on Immune Response in Healthy Infants

Start date: March 2009
Phase: N/A
Study type: Interventional

In this study the investigators hypothesized that the chronic intake of fructo-oligosaccharides would increase fecal immunoglobulin A (IgA) specific to poliovirus vaccination and bifidobacteria in infants.

NCT ID: NCT00941564 Completed - Infant Clinical Trials

Comparative Ca Absorption and Tolerance in Healthy Term Infants Fed Milk-based Formulas With Different Fat Blends

Start date: March 2010
Phase: Phase 4
Study type: Interventional

The objective is to assess the comparative calcium absorption and gastrointestinal (GI) tolerance in healthy normal term infants fed two commercially available powdered milk-based formulas which contain different fat blends.

NCT ID: NCT00938028 Completed - Infant Clinical Trials

Metabolome and Microbiomic in Fecal Samples

MicroMet
Start date: April 2009
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the effects of storage and handling on fecal samples collected for metabolomic, proteomic and microbiomic and analysis.

NCT ID: NCT00852904 Completed - Child Development Clinical Trials

National Children s Health Study

Start date: February 25, 2009
Phase:
Study type: Observational

Patterns of illness among children in the United States and other industrially developed nations have changed substantially during the past 100 years. Before and during the first half of the previous century, infectious diseases were the primary threat to children s health. In contrast, the major illnesses and disorders that impair health, growth, and development today are chronic conditions stemming from the complex interaction of environmental exposures and inherent genetic factors. The Children s Health Act of 2000 directed the National Institute of Child Health and Development to conduct a national longitudinal study of environmental influences on children s health in the United States. The act specified that the study extend from the prenatal period to adulthood and investigate the short-term and long-term influences of physical, chemical, biological, and psychosocial environmental exposures on children s health and development, including behavioral, emotional, and educational outcomes in addition to physical health. The National Children s Study (NCS) is an observational longitudinal study that will enroll and follow a nationally representative sample of approximately 100,000 U.S.-born children from before birth through their 21st birthday. The study will screen all households within selected areas of 105 locations (primarily counties). The major types of analysis of NCS data will include longitudinal exposure-outcome analysis, identification of causal pathways, analysis of neighborhood effects, evaluation of temporal effects within longitudinal data analysis of data from case-control data, and analysis of genomic data. Women in their first trimester of pregnancy will be invited to participate in the pre-pregnancy portion of the NCS. Women who are not pregnant but have a high probability of becoming pregnant will be asked to participate in the early pregnancy portion of the NCS. All other eligible women will be asked if the study can contact them periodically to assess their pregnancy status. They also will be asked to contact the NCS should they become pregnant. Women identified as pregnant within 4 years after initial screening will be invited to enroll in the NCS. The following information will be gathered: Mother s data and information - Questionnaire data interviewed and self-administered (e.g., demographics; current pregnancy history; reproductive history; medical conditions; health behaviors; doctor visits; medicines and supplements; housing characteristics; pesticides, product use; occupation, hobbies; depression, stress; social support; diet; time and activity) - Physical measures and clinical data (e.g., blood pressure, sonograms, height, weight, body measurements) - Biologic specimens (e.g., blood, urine, hair, saliva) - Environmental samples during home visits (e.g., dust, air, water) - Medical record abstraction Infant s data and information at birth - Cord blood and tissue samples of the placenta and umbilical cord - Standardized neurobehavioral exam - Physical measures and clinical data (e.g., length; weight; circumferences of head, arm, abdomen, thigh) - Meconium samples - Medical diagnoses and treatment by report - Selected Medical record abstraction

NCT ID: NCT00808756 Completed - Healthy Clinical Trials

Study on Fermentable Carbohydrates in Healthy Infants

BAMBINOL
Start date: September 2008
Phase: N/A
Study type: Interventional

The purpose of this project is to study the effect of fermentable carbohydrates in the nutrition of healthy infants.

NCT ID: NCT00732537 Completed - Respiratory Failure Clinical Trials

Inhaled Nitric Oxide by Oxygen Hood in Neonates

Start date: March 1999
Phase: Phase 4
Study type: Interventional

Inhaled nitric oxide (iNO) improves oxygenation in term infants with respiratory failure. However, iNO has been primarily used in infants receiving mechanical ventilation. This study is a pilot study to determine if iNO given into an oxygen hood is effective in improving oxygenation in term and near-term infants who have poor oxygenation but who are not yet mechanically ventilated.

NCT ID: NCT00624689 Completed - Infant Clinical Trials

Effects of Milk Fat Globule Membrane (MFGM) - Enriched Formula With Reduced Energy and Protein Content on Growth and Development

TUMME
Start date: March 2008
Phase: N/A
Study type: Interventional

Formula-fed infants differ from breast-fed infants in the growth pattern, risk for obesity and cardiovascular diseases, neurological development and morbidity in infections. The investigators' hypothesis is that a modified formula with reduced energy and protein content and enrichment with Milk Fat Globule Membrane (MFGM) containing bioactive proteins and phospholipids will reduce the difference between formula-fed and breast-fed infants.

NCT ID: NCT00507676 Completed - Asthma Clinical Trials

Lung Function and Structure in Healthy Infants and Infants With Recurrent Wheezing

Start date: October 2000
Phase: N/A
Study type: Observational

Infants will be enrolled into this study in one of three groups. First, there will be a group of full term infants with no history of wheezing. Second, there will be a group of infants receiving a ct scan that is non-respiratory related. Third, there will be a group of infants that are born full term but have a history of wheezing of at least 3 episodes. The three groups will be compared to see if there is a difference in lung function, lung structure and lung size. Besides comparing the testing results we will be evaluating environmental and inherited characteristics. There are 2 purposes of this study. The first purpose is: To determine whether asymptomatic groups of infants at high risk for wheezing (Environmental tobacco smoke (ETS) exposure, Fm Asthma, male Gender) have fixed or reversible airway narrowing. The second purpose of this study is: To determine the relative contributions of fixed and reversible airway narrowing in infants with recurrent symptomatic wheezing, and to determine whether fixed and reversible airway narrowing is related to ETS exposure, Fm Asthma, and male Gender.