Restoration of Arm Function in People With High-level Tetraplegia

Status Recruiting

Clinical Trial Summary

Functional electrical stimulation (FES) has been used to activate paralysed muscles and restore movement after spinal cord injury and stroke. This technology involves the application of low-level electrical currents to the nerves and muscles to cause muscle contraction where the user's ability to achieve that through voluntary means has been lost. Providing control of muscle contraction in a coordinated way can mean that users are able once again to produce functional movements in otherwise paralysed limbs. Routine clinical use is limited to the prevention of drop foot in the lower limb following stroke and occasional therapeutic use in the hand and shoulder. Systems providing functional reach and grasp, however, have not achieved clinical or commercial success. This project aims to develop methods for personalising assistive technology to restore arm function in people with high-level spinal cord injury. The investigators will use a combination of electrical stimulation to elicit forces in muscles no longer under voluntary control, and mobile arm supports to compensate for insufficient muscle force where necessary. The investigators will use computational models specific to an individual's functional limitations to produce patient-specific interventions. The project will be in three phases: building a model to predict the effects of electrical stimulation on a paralysed arm with arm support, development of methodologies using this model to optimise the arm support and stimulation system, and testing of stimulation controllers designed using this approach.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04102826
Study type	Interventional
Source	Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Contact	Neil Postans, PhD
Phone	00441691404532
Email	neil.postans@nhs.net
Status	Recruiting
Phase	N/A
Start date	September 29, 2021
Completion date	October 31, 2022

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04052009` - Locomotor Training in Individuals With Incomplete Spinal Cord Injury. A Pilot Study	N/A
Completed	`NCT01302522` - Mental Practice Impact on Gait and Cortical Organization in Spinal Cord Injury (SCI)	Phase 2
Recruiting	`NCT05975606` - Non-invasive Brain Stimulation Paired With FES Cycling Post SCI	N/A
Recruiting	`NCT04050696` - The Use of Electromagnetic Field (EMF) Treatment in Chronic Spinal Cord Injury (SCI) Patients	N/A
Active, not recruiting	`NCT06079138` - Tele-rehabilitation Using tDCS Combined With Exercise in People With Spinal Cord Injury	N/A
Recruiting	`NCT05605912` - Myosuit in Incomplete Spinal Cord Injury	N/A
Recruiting	`NCT06214546` - Effect of Different Support Systems on Gait	N/A
Completed	`NCT04340063` - Amplify Gait to Improve Locomotor Engagement in Spinal Cord Injury	N/A
Recruiting	`NCT05142943` - Effectiveness of Virtual Bodily Illusion Intervention in Upper Limb Motor Function in People With Incomplete Spinal Cord Injury.	N/A
Enrolling by invitation	`NCT05341466` - The Effect of Acute Intermittent Hypoxia on Motor Learning	N/A
Completed	`NCT04910412` - Effects of tDCS With Gait Training on Leg Performance in Incomplete Spinal Cord Injury	N/A
Recruiting	`NCT05726591` - Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders	N/A
Recruiting	`NCT03057652` - Algorithmic-Based Evaluation and Treatment Approach for Robotic Gait Training	N/A
Recruiting	`NCT05429736` - Activating Spinal Circuits to Improve Walking, Balance, Strength, and Reduce Spasticity	N/A
Completed	`NCT01851629` - Walking Adaptability Post-Spinal Cord Injury	N/A
Recruiting	`NCT01961557` - Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders	N/A
Recruiting	`NCT04977037` - A Telerehabilitation Program for SCI	N/A
Active, not recruiting	`NCT04809987` - Effectiveness of Virtual Gait System Intervention in Motor Function in People With Incomplete Spinal Cord Injury.	N/A
Not yet recruiting	`NCT06169657` - Comparison of Gait Training Methods in Sub-acute Stroke and Spinal Cord Injury
Not yet recruiting	`NCT05491837` - Effects of Intermittent Hypoxia in Upper and Lower Limb Functions in Persons With Incomplete Spinal Cord Injury	N/A