Clinical Trials Logo

Clinical Trial Summary

Functional electrical stimulation (FES) has been used to activate paralysed muscles and restore movement after spinal cord injury and stroke. This technology involves the application of low-level electrical currents to the nerves and muscles to cause muscle contraction where the user's ability to achieve that through voluntary means has been lost. Providing control of muscle contraction in a coordinated way can mean that users are able once again to produce functional movements in otherwise paralysed limbs. Routine clinical use is limited to the prevention of drop foot in the lower limb following stroke and occasional therapeutic use in the hand and shoulder. Systems providing functional reach and grasp, however, have not achieved clinical or commercial success. This project aims to develop methods for personalising assistive technology to restore arm function in people with high-level spinal cord injury. The investigators will use a combination of electrical stimulation to elicit forces in muscles no longer under voluntary control, and mobile arm supports to compensate for insufficient muscle force where necessary. The investigators will use computational models specific to an individual's functional limitations to produce patient-specific interventions. The project will be in three phases: building a model to predict the effects of electrical stimulation on a paralysed arm with arm support, development of methodologies using this model to optimise the arm support and stimulation system, and testing of stimulation controllers designed using this approach.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04102826
Study type Interventional
Source Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Contact Neil Postans, PhD
Phone 00441691404532
Email neil.postans@nhs.net
Status Recruiting
Phase N/A
Start date September 29, 2021
Completion date October 31, 2022

See also
  Status Clinical Trial Phase
Recruiting NCT04052009 - Locomotor Training in Individuals With Incomplete Spinal Cord Injury. A Pilot Study N/A
Completed NCT01302522 - Mental Practice Impact on Gait and Cortical Organization in Spinal Cord Injury (SCI) Phase 2
Recruiting NCT05975606 - Non-invasive Brain Stimulation Paired With FES Cycling Post SCI N/A
Recruiting NCT04050696 - The Use of Electromagnetic Field (EMF) Treatment in Chronic Spinal Cord Injury (SCI) Patients N/A
Active, not recruiting NCT06079138 - Tele-rehabilitation Using tDCS Combined With Exercise in People With Spinal Cord Injury N/A
Recruiting NCT05605912 - Myosuit in Incomplete Spinal Cord Injury N/A
Recruiting NCT06214546 - Effect of Different Support Systems on Gait N/A
Completed NCT04340063 - Amplify Gait to Improve Locomotor Engagement in Spinal Cord Injury N/A
Recruiting NCT05142943 - Effectiveness of Virtual Bodily Illusion Intervention in Upper Limb Motor Function in People With Incomplete Spinal Cord Injury. N/A
Enrolling by invitation NCT05341466 - The Effect of Acute Intermittent Hypoxia on Motor Learning N/A
Completed NCT04910412 - Effects of tDCS With Gait Training on Leg Performance in Incomplete Spinal Cord Injury N/A
Recruiting NCT05726591 - Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders N/A
Recruiting NCT03057652 - Algorithmic-Based Evaluation and Treatment Approach for Robotic Gait Training N/A
Recruiting NCT05429736 - Activating Spinal Circuits to Improve Walking, Balance, Strength, and Reduce Spasticity N/A
Completed NCT01851629 - Walking Adaptability Post-Spinal Cord Injury N/A
Recruiting NCT01961557 - Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders N/A
Recruiting NCT04977037 - A Telerehabilitation Program for SCI N/A
Active, not recruiting NCT04809987 - Effectiveness of Virtual Gait System Intervention in Motor Function in People With Incomplete Spinal Cord Injury. N/A
Not yet recruiting NCT06169657 - Comparison of Gait Training Methods in Sub-acute Stroke and Spinal Cord Injury
Not yet recruiting NCT05491837 - Effects of Intermittent Hypoxia in Upper and Lower Limb Functions in Persons With Incomplete Spinal Cord Injury N/A