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Implants clinical trials

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NCT ID: NCT06207578 Not yet recruiting - Implants Clinical Trials

Implants Placed With Crestal Sinus Approach Versus Osseodensification in Atrophic Posterior Maxilla

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

However, recently, most described techniques for posterior atrophic maxillary rehabilitation, are targeting more conservative, cost-effective and efficient methods for sinus elevation eliminating its lateral access. The aim of the present study is to evaluate and compare the long-term implant stability for implants placed by the novel crestal sinus approach versus osseodensification using Densa-bur in Atrophic Posterior Maxilla.

NCT ID: NCT04741906 Recruiting - Cancer Clinical Trials

Outcome of Dental Implant Therapy in Patients Treated With Antiresorptive Medication

Start date: August 1, 2017
Phase:
Study type: Observational [Patient Registry]

Aim of the study is to examine the feasibility of dental implant insertion in patients receiving high, adjuvant and low dose > 4 years.

NCT ID: NCT04205929 Active, not recruiting - Bleeding Clinical Trials

Use of Curcumin to Treat Unfavorable Bleeding Patterns in Contraceptive Implant Users

Start date: April 15, 2020
Phase: Phase 4
Study type: Interventional

The investigators plan to study the effects of curcumin, the active ingredient in the spice turmeric, on the irregular bleeding experienced by women who use the contraceptive implant.

NCT ID: NCT02903121 Completed - Bleeding Clinical Trials

Treatment of Unfavorable Bleeding Patterns in Contraceptive Implant Users

Tamoxifen/BTB
Start date: January 20, 2017
Phase: Phase 4
Study type: Interventional

The etonogestrel (ENG) subdermal contraceptive implant (ENG implant) is a highly effective method of preventing pregnancy, but it has bleeding side effects that make it unappealing for many women. The only study to demonstrate a sustained reduction in bleeding lasting for two months was the selective estrogen receptor modulator (SERM) tamoxifen in users of the levonogestrel (LNG) contraceptive implant. Based on the investigators encouraging preliminary data of tamoxifen and ENG implant users, the investigators plan to perform additional studies on the impact of tamoxifen on the breakthrough bleeding experience by ENG implant users.

NCT ID: NCT02661204 Recruiting - Breast Cancer Clinical Trials

Diagnostic Performance of an Automated Breast Ultrasound System (ABUS)

Start date: January 2016
Phase:
Study type: Observational

The purpose of this study is to evaluate the diagnostic performance of a new ABUS system among 4 different population: Population A: women undergoing screening for familial or genetic predisposition for breast cancer. Population B: women with newly diagnosed breast cancer. ABUS performance will be compared to breast MRI in the pre-operative assessment of breast cancer extent. Population C: women with BI-RADS 3 or 4 lesions in a routine breast imaging examination. ABUS will be evaluate as a problem-solving tool. Population D: women undergoing breast MRI for the assessment of breast implants integrity. ABUS performance will be compared to breast MRI.

NCT ID: NCT02566694 Recruiting - Implants Clinical Trials

Analysis of Specimens From Patients With Orthopaedic Implants

Start date: March 2015
Phase: N/A
Study type: Observational

The investigators aim to determine the cause of failure of orthopaedic implants using multi-disciplinary analysis of data from patients who have undergone revision.

NCT ID: NCT02262065 Completed - Allergy Clinical Trials

Risk Factors for Enhanced Inflammation to Arthroplasty Wear Particles: Analysis of Cytokine Production and Polymorphisms

Start date: July 2012
Phase:
Study type: Observational

Assessment of cytokine polymorphisms in 100 patients with aseptic complications to arthroplasty as compared to 100 symptom-free arthroplasty patients. In selected patients additional in-vitro cytokine release assay with peripheral blood mononuclear cells (PBMC) stimulated with different wear particles.

NCT ID: NCT01971268 Not yet recruiting - Bone Loss Clinical Trials

Compare the Success Rate of T3 Dental Implant (Biomet 3I) With or Without Platform-switch Concept

Start date: January 2014
Phase: N/A
Study type: Observational

In patients that received a T3 (Biomet 3I) dental implant, does the use of platform-switch concept compared to the use of platform-matched concept, refrain marginal bone loss during osseointegration phase (t=12 weeks =T1) and from then to final rehabilitation (t= placement of the final restoration = at 18 weeks=T2)

NCT ID: NCT01570543 Withdrawn - Implants Clinical Trials

MRI Scanning of People With MR Safe Orthopedic Implants That Are Made of Metal

MRI
Start date: March 2012
Phase: N/A
Study type: Observational

The purpose of the study is to improve image quality, increase speed of scanning and to see how well certain products test by scanning people who have an orthopedic hip or knee metallic implant.

NCT ID: NCT01517737 Recruiting - Implants Clinical Trials

Immunology of Failing Metal-on-Metal Hip Replacement

Start date: January 2012
Phase: N/A
Study type: Observational

Metal-on-metal total hip replacement (MoM THR) has been targeted at younger patients with anticipated long-term survival since the bearing surfaces wear less than the traditional metal-on-plastic (MoP) replacements. However, the production of metal ions as a result of the wear is a concern because of the possible toxicity to cells. In Norwich England a number of different metal-on-metal implants have been trialed of which one, the Ultima TPS, has had very poor results. A total of 545 patients have had 652 MoM THRs with the Ultima TPS of whom more than 20% have now been revised. There is an ongoing MHRA program to screen for problems using MRI scans with a technique developed in Norwich. Investigations so far show massive corrosion in the implants with a catastrophic immune response causing death of cells. This may include death of bone leading to fracture. In a third of patients revised there has been pain but normal plain X-rays. In some patients without pain who have been screened there are abnormal changes on an MRI scan. We wish to investigate the immune cells in patients to find out why this has happened. The study will include patients coming for a new hip to act as a comparator, as well as those with a MoM THR and patients being revised with MoM THRs, and MoP THRs. We shall also investigate patients with other MoM THRs opportunistically.