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Immunity clinical trials

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NCT ID: NCT06337539 Not yet recruiting - Depression Clinical Trials

Precision Psychiatry for Depression: Immune Response and Affective Symptoms as Predictors of Response to Antidepressants

LYMPHODEP
Start date: April 1, 2024
Phase:
Study type: Observational

Objectives: To identify in patients with major depression different peripheral markers of neuroinflammation in relation to affective symptoms (anxiety, depression, irritability), fatigue and cognitive symptoms; and its relationship with the response to antidepressant treatment with selective serotonin reuptake inhibitors (SSRIs). Methodology: This is a prospective observational cohort study in patients with major depression naturally subjected to treatment with SSRIs. For this, 30 patients with major depression attended in the Outpatient Psychiatry Consultations will be selected. All of them will be evaluated at baseline and after 3 months of treatment, collecting demographic and clinical variables, Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5) psychiatric diagnoses, psychopathological scales and immunological and biochemical variables. The correlation between immunological markers and affective and cognitive symptoms at baseline, as well as their variation with treatment, will be analyzed. A group of 20 healthy subjects will be used as a control group. Subsequently, a bivariate comparative analysis will be carried out, where the statistically significant or marginally significant variables associated with psychopathological variables will be used to build a multivariate binary logistic regression model.

NCT ID: NCT06229262 Not yet recruiting - Cognition Clinical Trials

Immune and Cognitive Benefits of Mango Intake in Young Adults

Start date: June 2024
Phase: N/A
Study type: Interventional

The main objectives of our proposed study are to determine the effects of mango consumption on immune and cognitive functions in free-living college going young adults aged 18-30 years

NCT ID: NCT06121362 Withdrawn - Immunity Clinical Trials

Effect of Protocatechuic Acid on Biochemical Markers of Immunity Status in Healthy Adults

Start date: March 2024
Phase: N/A
Study type: Interventional

The purpose of this voluntary research study is to determine if a dietary supplement containing a substance called protocatechuic acid (PCA) can change markers in blood related to immunity (a body's natural ability to fight diseases and infections) over a 14-day study period. Blood tests and other assessments will be completed before and after taking either 1,000 milligrams a day of protocatechuic acid (PCA) or a placebo (i.e., a sugar pill) for 14 days.

NCT ID: NCT05682573 Recruiting - COVID-19 Clinical Trials

Study on Immune Status of Patients With COVID-19

Start date: January 5, 2023
Phase:
Study type: Observational

This study is a prospective cohort study aimed to clarify the continuous immune state changes of patients with COVID-19. Investigators include the patients admitted to the hospital within one week after the onset of COVID-19. 10ml of patients' blood was collected day 1, day 7, day 14 , and day 20 after the patients admitted to the hospital. The blood inflammatory factors, immune related molecules, and immune cells were detected to determine the changes of patients' immune status. The impact of immune status changes on prognosis and quality of life in later follow-up period was evaluated by various questionnaires and evaluation scales.

NCT ID: NCT05589233 Completed - COVID-19 Clinical Trials

COVID-19 Vaccination AZV 2021-2023

Start date: January 1, 2021
Phase:
Study type: Observational

The study is aimed at the clinical and laboratory characteristics of patients with completed vaccination against SARS-CoV-2 admitted to the hospital in the standard ward and intensive care unit due to the severe course of COVID-19.

NCT ID: NCT05585021 Completed - Immunity Clinical Trials

Clinical Study on the Effect of Probiotic Compound Powder on the Immunity Improvement of Preschool Children

Start date: October 19, 2022
Phase: N/A
Study type: Interventional

This is a randomized controlled trial, to evaluate the effect of WONDERLAB Probiotic Compound Powder on improving immunity of preschool children

NCT ID: NCT05324800 Active, not recruiting - Immunity Clinical Trials

the Efficacy and Safety of Curcuma Longa Extract Mixture on Immune Enhancement

Start date: February 4, 2022
Phase: N/A
Study type: Interventional

This study was conducted to investigate the efficacy and safety of Curcuma longa extract mixture on immune enhancement

NCT ID: NCT05190237 Completed - Immunity Clinical Trials

the Efficacy and Safety of Fermented Soybean(Doenjang Powder) on Intestinal Microflora and Immune Enhancement.

Start date: November 19, 2021
Phase: N/A
Study type: Interventional

This study was conducted to investigate the efficacy and safety of Fermented soybean(Doenjang powder) on intestinal microflora and immune enhancement.

NCT ID: NCT05162820 Completed - Smoking, Cigarette Clinical Trials

Impact of Solarplast® on Immunity in Active Smokers and Non-smokers

Start date: October 22, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the impact of Solarplast treatment on measures of oxidative stress, immune function, skin appearance, and associated measures in 60 men and women, consisting of both cigarette smokers and nonsmokers. The hypothesis is that the Solarplast treatment will reduce oxidative stress biomarkers and favorably impact immune measures and both perceived and quantifiable measures of skin health, in both smokers and non-smokers, with a greater impact observed in smokers. Photographic analyses like the Pear Plus 3D system have been developed for clinical use for monitoring skin health.

NCT ID: NCT05117385 Recruiting - Healthy Subject Clinical Trials

The Effect of the Consumption of 4 Botanical Extracts on Immunity in Healthy Adults (B-4-Immune)

B-4-Immune
Start date: November 22, 2021
Phase: N/A
Study type: Interventional

This study will evaluate the capacity of botanical extracts to modulate immune mechanisms compared to a placebo group in healthy volunteers.