Unnecessary Mastectomy Due to False Size Prediction by Preoperative Imaging Studies in Breast Cancer — PUMP  

Breast Cancer Clinical Trial

Official title: The Percentage of Unnecessary Mastectomy Due to False Size Prediction by Preoperative Imaging Studies in Breast Cancer Patients Who Underwent Neoadjuvant Chemotherapy

Status Active, not recruiting

Clinical Trial Summary

• The surgical method for breast cancer is determined according to the size and location of the remaining lesions after prior chemotherapy.

• There are many patients who were able to undergo partial resection when confirming the final results of patients who underwent total resection after prior chemotherapy.

• Therefore, we would like to investigate whether it is effective to make decisions based on the results of pre-operative tests after prior chemotherapy.

Clinical Trial Description

In a study published by Jennifer F. et al., sensitivity to lesions remaining after prior chemotherapy of breast magnetic resonance imaging was measured as 83%, specificity 47%, PPV 47%, NPV 83%, and accuracy 74%. have.

Most of the preoperative examinations after prior chemotherapy have the most confidence in the results of breast magnetic resonance imaging, but there will be other factors to predict this result as there will be differences in the actual postoperative pathology results. .

After prior chemotherapy, total resection was performed, and cases where partial resection is possible in the postoperative pathologic results are prospectively identified and compared and analyzed. ;

Related Conditions & MeSH terms

• Breast Cancer
• Breast Neoplasms
• Chemotherapy Effect
• IMAGE
• Surgery

• NCT number: NCT04689529
• Study type: Interventional
• Source: Seoul National University Hospital
• Status: Active, not recruiting
• Phase: N/A
• Start date: March 23, 2018
• Completion date: December 31, 2023