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Idiopathic Scoliosis clinical trials

View clinical trials related to Idiopathic Scoliosis.

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NCT ID: NCT01795495 Completed - Clinical trials for Idiopathic Scoliosis

Methadone vs Magnesium in Spinal Fusion

Start date: September 2013
Phase: Phase 2
Study type: Interventional

Significant pain may occur following posterior spinal fusion despite the use of conventionally accepted techniques including patient controlled analgesia. If detected, a significant reduction in opioid requirements may lead to improved patient satisfaction and decreased opiate side effects. The current study would use a prospective, randomized trial investigating the efficacy of one of 2 regimens as adjuncts to intraoperative anesthesia and postoperative analgesia, along with a third control group. The patients would be randomized to receive remifentanil plus a single intraoperative dose of methadone; remifentanil plus a bolus followed by an infusion of magnesium; or remifentanil alone. In addition, the two medications being studied might make it easier to determine the efficacy of neurophysiologic monitoring including somatosensory evoked potential (SSEP) (amplitude and latency) and motor evoked potential (MEP) (mA) required to elicit the response. The purpose of this study would be to explore the effects of intraoperative methadone vs magnesium on intraoperative anesthetic requirements, postoperative opioid requirements, the efficacy of neurophysiologic monitoring including SSEP and MEP, inspired concentration of desflurane, remifentanil, and the need for intraoperative supplemental agents to control blood pressure.

NCT ID: NCT01772459 Completed - Adolescent Clinical Trials

Paper vs. Internet

P vs I
Start date: August 2010
Phase: N/A
Study type: Observational

Research has shown that questionnaires completed on the internet have the potential to provide more complete and honest data with fewer errors in a more efficient manner than questionnaires completed using the paper and pencil format. Despite the numerous advantages of internet-administered questionnaires, it is important to make sure that the internet questionnaires will yield comparable results to the well-established paper and pencil versions. No one has studied internet administration of scoliosis specific questionnaires in adolescents with scoliosis. The investigators will test whether the internet administration of scoliosis questionnaires is as reliable as the traditional paper and pencil version. The investigators predict that the internet-administered questionnaire will provide the same reliability as the paper-administered questionnaires.

NCT ID: NCT01761305 Active, not recruiting - Clinical trials for Idiopathic Scoliosis

Trial on Three Treatments for Scoliosis

CONTRAIS
Start date: January 2013
Phase: N/A
Study type: Interventional

Idiopathic scoliosis is a three-dimensional structural deformity of the spine that occurs in children. Recent reviews on bracing and exercise treatment have provided some evidence for effect of these interventions. The purpose of this study is to compare the effectiveness of night time bracing, scoliosis specific exercises and physical activity prescription in adolescents with idiopathic scoliosis.

NCT ID: NCT01549873 Completed - Clinical trials for Idiopathic Scoliosis

Anesthesia During Neurophysiologic Monitoring in Scoliosis Patients

Start date: January 2012
Phase: N/A
Study type: Interventional

When patients have spinal surgery, electrodes are placed on the body to measure motor evoked potentials (MEP) and somatosensory evoked potentials (SSEP). Many hospitals only use IV anesthesia because they feel that measuring MEP and SSEP is easier using IV anesthesia. At this hospital the investigators typically use inhaled anesthesia and are able to successfully measure MEP and SSEP. This is a study to find out if one method of anesthesia is better than the other for measuring MEP and SSEP.

NCT ID: NCT01325493 Completed - Spondylolisthesis Clinical Trials

Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia

KPSF
Start date: January 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to: 1. Establish whether ketamine can decrease opioid consumption and modulate the onset of opioid tolerance and prevent opioid-induced hyperalgesia in pediatric subjects, ages 10 years to 18 years, undergoing posterior spinal fusion and instrumentation.

NCT ID: NCT01019109 Completed - Clinical trials for Idiopathic Scoliosis

Scoliosis Surgery Using the PASS® LP System

Start date: May 2010
Phase:
Study type: Observational

The purpose of this study is to find out the outcomes of using the PASS LP System to correct idiopathic scoliosis. This system is a unique set of spinal instrumentation used to surgically correct the rotation and deformity of the spine that is caused by scoliosis. Also, this study wants to find out the effects this system has on the physical appearance and quality of life for patients with scoliosis.