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Ibuprofen clinical trials

View clinical trials related to Ibuprofen.

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NCT ID: NCT06232785 Completed - Clinical trials for Postoperative Nausea and Vomiting

Gynecologic Endoscopic Surgery of Female Motion Sickness Patients

Start date: February 1, 2022
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to compare the analgesic effect of sufentanil and ibuprofen and the incidence of vomiting, and to choose better postoperative analgesic drugs for motion sickness patients.in describe participant population. The main questions it aims to answer are: - Whether this anesthesia method can meet the analgesic needs of gynecological laparoscopic surgery. - Whether this anesthesia method can reduce the incidence of nausea and vomiting in patients with motion sickness after gynecological laparoscopic surgery. Participants will use target-controlled infusion anesthesia combined with 0.8g ibuprofen injection. Researchers will compare with use of target-controlled infusion combined with sufentanil to see if the incidence of nausea and vomiting is higher.

NCT ID: NCT06064175 Completed - Analgesia Clinical Trials

"Management of Low Back Pain in the Emergency Department With Different Analgesic Dosages"

Start date: January 1, 2022
Phase: Phase 4
Study type: Interventional

The Management of Low Back Pain in the Emergency Department Worldwide, low back pain is one of the most prevalent musculoskeletal disorders, and it constitutes one of the primary complaints in emergency departments. A review of the literature reveals studies comparing ibuprofen to various agents (such as paracetamol, nimesulide, acetaminophen), and these studies suggest the use of ibuprofen due to its similar or superior efficacy and its safety profile. However, there is a lack of randomized controlled double-blind comparisons between the commonly recommended single doses of ibuprofen, which are 400 mg and 800 mg. Therefore, the objective of our planned study is to compare the analgesic efficacy of ibuprofen in the forms of 400 mg and 800 mg, which can be administered as a single dose, in the treatment of acute mechanical low back pain, as recommended in all guidelines.

NCT ID: NCT05971186 Completed - Clinical trials for Dysmenorrhea Primary

Dark Chocolate, Coconut Water, and Ibuprofen in Managing Primary Dysmenorrhea

Start date: June 30, 2022
Phase: Phase 2
Study type: Interventional

Dysmenorrhea, the painful condition experienced by women during menstruation, affects a significant proportion of women worldwide and often leads to decreased productivity. Various pharmacological and non-pharmacological treatments are available for pain relief, but information on their effectiveness, particularly regarding green coconut water, dark chocolate, and Ibuprofen, remains limited. This study aimed to compare the effectiveness of green coconut water, dark chocolate bars, and Ibuprofen in reducing the intensity of primary dysmenorrhea. A randomized controlled trial with a quantitative design was conducted, involving 45 participants randomly assigned to receive either 330 ml of green coconut water, 35 grams of 70% dark chocolate, or 400 mg Ibuprofen. Pain intensity was measured before and after treatment.

NCT ID: NCT05782608 Completed - Colorectal Cancer Clinical Trials

IV Ibuprofen vs Ketorolac in Post Operative Pain in Colorectal Cancer Surgeries in Obese Patient

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to assess the Efficacy of IV Ibuprofen and Ketorolac in the Management of Postoperative Pain in obese patients Following abdominal cancer surgery.

NCT ID: NCT05695664 Completed - Postoperative Pain Clinical Trials

Postoperative Analgesic Effects of Ibuprofen Versus Ketorolac in Patients Undergoing in Orthopedic Surgery

Start date: August 1, 2021
Phase: Early Phase 1
Study type: Interventional

Objectives: To compare the postoperative analgesic effects of ibuprofen versus ketorolac in patients undergoing orthopedic surgery at Combined Military Hospital, Rawalpindi. Study design: Randomized controlled trial Setting: Department of Anasthesiology, Combined military Hospital, Rawalpindi Duration of study:6 months (01st August 2021 to 31st January 2022) Material and methods: After ethical approval, 100 patients in randomly divided two equal groups (A and B) were selected. In group A, 800 mg IV ibuprofen while in group B, 30 mg IV ketorolac was given within 30 min of skin closure after orthopedic surgery. The pain was assessed via visual analogue scale postoperatively. The SPSS version 25 was used for analysis of data. P value ≤ 0.05 was considered as significant.

NCT ID: NCT02243254 Completed - Pain, Postoperative Clinical Trials

Prevention of Remifentanil-induced Postoperative Hyperalgesia With Intravenous Ibuprofen

Start date: July 2014
Phase: N/A
Study type: Interventional

Postoperative hyperalgesia has been reported after intraoperative administration of small or high-dose remifentanil. Cyclooxygenase inhibitor exhibit preventive effects on the development of opioid-induced hyperalgesia. The aim of this study is to evaluate the preventive effect of intravenous ibuprofen (Caldolor®) on remifentanil-induced hyperalgesia

NCT ID: NCT01092676 Completed - Ankle Injuries Clinical Trials

Regular vs Intermittent Dose Ibuprofen for the Treatment of Ankle Sprains in Children

Start date: February 2010
Phase: N/A
Study type: Interventional

Ankle sprains are common in children, and optimal pain management has not been determined. We hypothesize that children age 7-17 years of age with acute ankle sprain randomized to receive regular dose ibuprofen will show a greater improvement in degree of pain,disability,swelling and tenderness four days following injury as compared to children who take ibuprofen only intermittently for pain relief during the same time period.