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Hypophosphatasia clinical trials

View clinical trials related to Hypophosphatasia.

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NCT ID: NCT04189315 Withdrawn - Hypophosphatasia Clinical Trials

Relieving Burden of Hypophosphatasia in Adults With Functional Impairment Due to Chronic Disease

REBUILD
Start date: April 2020
Phase: Phase 4
Study type: Interventional

The study will evaluate safety, tolerability, efficacy, pharmacokinetics, and pharmacodynamics of 2 different doses (approved dose and lower dose) of asfotase alfa in adult participants with pediatric-onset hypophosphatasia (HPP).

NCT ID: NCT02603042 Withdrawn - Clinical trials for Defective Mineralization

Biomarker for Hypophosphatasia Disease (BioHypophos)

BioHypophos
Start date: August 20, 2018
Phase:
Study type: Observational

Development of a new MS-based biomarker for the early and sensitive diagnosis of Hypophosphatasia disease from plasma

NCT ID: NCT00894075 Withdrawn - Hypophosphatasia Clinical Trials

Safety and Efficacy Study of ENB-0040 in Juvenile Patients With Hypophosphatasia (HPP)

Start date: July 2009
Phase: Phase 2
Study type: Interventional

This Clinical Trial is being conducted to study Hypophosphatasia (HPP), a bone disorder caused by gene mutations or changes. These gene mutations cause low levels of an enzyme needed to harden bone. The purpose of this study is to test the safety of the study drug called ENB-0040 and see what effects is has on human juveniles and HPP.