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Hyperventilation clinical trials

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NCT ID: NCT05488301 Completed - Hyperventilation Clinical Trials

Effects of Chest Physiotherapy in Hyperventilation Syndrome

SHV
Start date: October 1, 2021
Phase:
Study type: Observational [Patient Registry]

Hyperventilation syndrome induce dyspnea and altered quality of life. the aim of this study is to assess the impact of chest physiotherapy on hyperventilation syndrome' symptoms

NCT ID: NCT05224830 Completed - COVID-19 Clinical Trials

Relationship Between Hyperventilation Syndrome and SARS-CoV-2 Infection

Hypercovid
Start date: January 1, 2021
Phase:
Study type: Observational

Following an acute COVID-19 infection, many patients suffer from long lasting physical symptoms that may greatly impair quality of life. Persisting dyspnea and other functional respiratory complaints could evoke Hyperventilation Syndrome (HVS) as a putative contributor of the long-COVID presentation in COVID-19 survivors. We aimed to assess the possible relationship between a HVS and previous acute SARS-CoV-2 infection.

NCT ID: NCT05189158 Completed - Hypoxia Clinical Trials

Ventilatory Responses to Hypercapnic and Hypoxic Conditions in Hyperventilants

Start date: October 15, 2021
Phase: N/A
Study type: Interventional

For almost a century, many hypotheses have converged on the idea of altered chemosensitivity in patients suffering from hyperventilation syndrome (HVS). Given the evolution of current technical equipment and the ability to maximise true positives in HVS ( using the revised hyperventilation provocation test), it seems reasonable to investigate central and peripheral chemosensitivities in HVS subjects.

NCT ID: NCT05100290 Completed - Clinical trials for Hyperventilation Syndrome

Predictive Properties of the Hyperventilation Provocation Test for the Diagnosis of the Hyperventilation Syndrome

Start date: June 15, 2018
Phase:
Study type: Observational

The Hyperventilation Provocation Test (HPTest) associated with end-tidal CO2 pressure (PETCO2) measurement is a diagnostic tool for idiopathic hyperventilation syndrome (HVS). However, interpretation of HPTest remains unclear regarding the relevant PETCO2 values to consider and the occurrence of subjective symptoms. This case-control study aims to identify accurate HPTest measurements for the diagnosis of HVS, regardless of symptoms occurrence.

NCT ID: NCT04514887 Completed - Clinical trials for Laparoscopic Gastric Sleeve Surgery

Mild Intraoperative Hyperventilation to Decrease Post-op. Shoulder Pain After LSG

Start date: June 16, 2019
Phase: N/A
Study type: Interventional

Shoulder pain is common after laparoscopic surgeries. multiple maneuvers are in use to decrease its incidence with variable results. This study aims to investigate the effect of mild hyperventilation to an End-tidal CO2 level of 30-32 mmHg on the occurrence of postoperative shoulder pain. This is carried out through a comparison of the incidence of postoperative shoulder pain an intervention group to that in a control one with a normal End Tidal CO2 35-40 mmHg). controlling for all other variables.

NCT ID: NCT04254952 Completed - Clinical trials for Hyperventilation Syndrome

Turkish Version of Nijmegen Questionnaire

Start date: September 15, 2019
Phase:
Study type: Observational

The study aims to provide Turkish version of Nijmegen Questionnaire for the evaluation of respiratory dysfunction in asthmatic subjects. The incidence of hyperventilation syndrome in asthmatic patients can be determined with the results of the study.

NCT ID: NCT04232059 Completed - Craniotomy Clinical Trials

The Effect of Different Ventilation Strategies on Cerebral Oxygenation Using Near Infrared Spectroscopy (NIRS) in Pediatrics Undergoing Posterior Fossa Tumor Surgery

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the changes of cerebral oxygen saturation during hyperventilation and normo-ventilation (using near-infrared spectroscopy) in pediatrics undergoing posterior fossa tumor resection.

NCT ID: NCT04132427 Completed - Clinical trials for Pitt Hopkins Syndrome

MTT for Children With Both Pitt Hopkins Syndrome and Gastrointestinal Disorders

Start date: September 30, 2019
Phase: Phase 2
Study type: Interventional

The investigators propose to investigate Microbiota Transfer Therapy (MTT) for treating patients with Pitt Hopkins Syndrome (PTHS) and gastrointestinal problems similar to Irritable Bowel Syndrome (IBS). MTT involves a combination of 10 days of oral vancomycin (an antibiotic to kill pathogenic bacteria), followed by a bowel cleanse, followed by 12 weeks of Fecal Microbiota (FM).

NCT ID: NCT04098731 Completed - Fibromyalgia Clinical Trials

Evaluation of Respiratory Function in Fibromyalgia

Start date: June 28, 2018
Phase:
Study type: Observational

This study will evaluate respiratory function in people with fibromyalgia and whether or not breathing patterns in this patient group can be explained by stress, emotional or biomechanical variables. In addition, examine the relationship between physical ability and lactate values.

NCT ID: NCT04091542 Completed - Breast Cancer Clinical Trials

Hyperventilation and Oxygenation to Prolong Breath Hold in Breast Cancer Irradiation Treatment

HOBBIT
Start date: March 15, 2019
Phase: N/A
Study type: Interventional

With the HOBBIT trial, the investigators want to develop a technology that allows volunteers to hold their breath for a long time. This technique will then be taught to patients with breast cancer to be able to hold their breath long-term during the irradiation. After all, research has shown that the heart is in a better position when the patient enters her breath after a deep inhalation, as a result of which there is less unwanted radiation of the heart. To develop this technique the investigators use healthy volunteers, who are asked several times to hold their breath as long as comfortable. Before the respiratory arrest the investigators allow these volunteers to hyperventilate, administer oxygen and cause hyperinflation of the lungs. The volunteers come back four times, on four consecutive days. The first day they receive a short training. Afterwards oxygen is administered for a few minutes while the volunteers are asked to hyperventilate. Afterwards, by using the learned technique, they must hold their breath for as long as possible, comfortably. They should hold their breath 3 times in total with a short break in between. The following days there is always a change in the preparation protocol, compared to the previous study. Different parameters in the protocol will be changed for different groups of volunteers, this is based on randomization. In this way the effect of different parameters in the preparation of the AHS can be investigated. The investigators will use this information to develop a new protocol for extending the duration of breathing to two minutes and thirty seconds for use during radiotherapy treatment. The method for finding the optimal technique is iterative optimization. This method follows a process of development, testing, feedback and redevelopment cycles. Iteratively, these cycles of development use the prior research to further elaborate the most promising discoveries and drop paths that do not produce the desired result. During the development The investigators listen to the input of different people: doctors, nurses, support staff, engineers and the participants, to guarantee the usability of the technique on the radiotherapy device. Once the researchers think they have found a solution that meets all the conditions, a group of untrained volunteers are asked to implement the technique. With this the investigators validate the technique for later use in breast cancer patients.