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Hypertrophy clinical trials

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NCT ID: NCT04056715 Completed - Atrial Fibrillation Clinical Trials

Extended ECG Monitoring in HCM Patients

EXAMINE-HCM
Start date: January 14, 2020
Phase:
Study type: Observational

The purpose of this study is to determine, among a large cohort of 300 consecutive patients with hypertrophic cardiomyopathy, if extended ambulatory monitoring using the iRhythm Technologies, Inc. Zio XT device results in identifying a greater burden of nonsustained ventricular tachyarrhythmia (nsVT) compared to current ACCF/AHA guideline recommended 48-hour monitoring.

NCT ID: NCT04016064 Completed - Clinical trials for Gingival Enlargement

Temperature and Healing in Treatment of Gingival Enlargement

Start date: January 1, 2012
Phase: N/A
Study type: Interventional

Aim: Gingival enlargement is a common clinical condition which requires surgical approaches to alleviating these enlargement areas. The aim of this study was to investigate epithelization, gingival temperature, inflammation and pain levels in post-operative healing process in 4 different gingivectomy techniques including Er:YAG laser, Nd:YAG laser, electrosurgery and conventional gingivectomy in treatment of chronic inflammatory gingival enlargements. Material and Method: A split-mouth designed study was conducted on 37 systemically healthy patients consisting of 19 females and 18 males, who had gingival enlargement areas on the left and right of maxillary and mandibular anterior regions. Gingival crevicular fluid (GCF) samples were collected, clinical periodontal parameters and gingival temperature levels were recorded at baseline and in the postoperative period. The gingival temperature was measured during surgical procedures. Gingival temperature and epithelization levels in 3rd, 7th, 10th and 15th days; GCF levels in 15th, 30th, and 90th days and pain levels in 2nd and 8th hours and between 1st-7th days of post-operative healing process were evaluated.

NCT ID: NCT04000750 Completed - Muscle Hypertrophy Clinical Trials

Time-Restricted Eating and Muscle Hypertrophy

Start date: June 24, 2019
Phase: N/A
Study type: Interventional

The purpose is to examine the effects of time-restricted eating (TRE; consuming all calories within an 8-hour period each day) vs. normal eating (CON; consuming same kcals and protein as TRE, but during a 10-13 hr eating window each day) during 8 weeks of resistance exercise on body composition and muscle mass (whole muscle and single fiber), muscular performance, anabolic protein signaling, single muscle fiber characteristics, and the gut microbiome in well-trained young men and women.

NCT ID: NCT03993483 Completed - Muscle Strength Clinical Trials

Upper Versus Lower Limb Responses to Higher Versus Lower Load Resistance Training in Young Men

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

Recent research suggests that performing resistance exercise training with relatively light loads is equally as effective at increasing muscle mass and muscle strength as performing resistance exercise training with relatively heavy loads. Whether or not performing resistance exercise with relatively heavy loads or light loads is equally as effective between the upper- and lower-body within the same individual has never been investigated. Given the substantial individual variance in resistance exercise training-induced changes in muscle mass and strength, this study is designed to quantify the relative influence that extrinsic training variables (e.g., load), as opposed to intrinsic muscle-based predisposition, has on resistance training-induced changes in muscle mass and muscle strength.

NCT ID: NCT03991117 Completed - Muscle Hypertrophy Clinical Trials

Lower and Higher Load Resistance Exercise Protocols: Acute Muscle Activation and Skeletal Muscle Hypertrophy

Start date: January 4, 2016
Phase: N/A
Study type: Interventional

How much weight an individual lifts per workout does not dictate the relative increase in muscle size the individual gains following weeks of training, which is contrary to current strength training dogma. Specifically, researchers have concluded that so long as an individual performs resistance exercise with maximum effort, it is not necessary to lift with relatively heavy loads. However, other laboratories, on the basis of surface electromyography measurements, have challenged the thesis that lighter loads can result in the hypertrophy of larger, type II muscle fibres. Therefore, the purpose of this study was to combine surface electromyography measurements with direct measurements of muscle fibre activation to see if muscle fibre activation was truly dependent on load. The investigators hypothesized that all muscle fibres would be activated when the resistance exercise was performed with maximal effort.

NCT ID: NCT03988049 Completed - Clinical trials for Acne Scars - Mixed Atrophic and Hypertrophic

Comparison of 1,550 and 755 Laser in a Split-face Trial

Start date: March 8, 2017
Phase: N/A
Study type: Interventional

Clinical Trial comparing the 1,550-nanometer fractionated photothermolysis system laser to the 755 nanometer picosecond laser using a split-face (Right-Left) comparison. Patients will receive laser treatments at week 0, week 4, and week 8. Photographs will be taken prior to laser treatment at each visit, and at the week 24 follow-up visit. Photographs will be reviewed by blinded assessors to rate each side of the face and change from baseline photos.

NCT ID: NCT03986346 Completed - Hypertrophic Scar Clinical Trials

The Vascularity Changes of Scars With Laser Therapy

Start date: May 31, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to explore the effects of pulsed dye laser on managing scar vascularity and thickness.

NCT ID: NCT03953989 Completed - Clinical trials for HCM - Hypertrophic Non-Obstructive Cardiomyopathy

Effects of Ranolazine on Coronary Microvascular Dysfunction in Patients With Hypertrophic Cardiomyopathy

Start date: October 2016
Phase: Phase 2
Study type: Interventional

To demonstrate the efficacy of ranolazine in improving coronary microvascular and diastolic dysfunction in patients affected by HCM evaluating changes in maximum (i.e. during dipyridamole-induced coronary vasodilatation) myocardial blood flow (MBF) measured by PET at baseline and after 4 months of treatment with ranolazine in patients with non obstructive HCM.

NCT ID: NCT03920553 Completed - Clinical trials for Frenulum; Hypertrophy, Lip

Hyaluronic Acid Application Following Frenectomy

Start date: January 2, 2019
Phase: N/A
Study type: Interventional

This randomized clinical study aimed to compare the outcomes of the laser-assisted frenectomy with and without topical hyaluronic acid application to evaluate the effect of HA on secondary wound healing after frenectomy surgery. The study included a total of sytemically healthy 40 patients , with high labial frenulum attachment requiring frenectomy. Following laser-assisted frenectomy operation HA gel was applied to the wound surface in the test group, and no application was made to the control group The HA application was made topically to completely cover the surgical area on days 3, 7, and 14 postoperatively. Photographs of the operation area were taken on days 3, 7, and 14. The changes in the area measurements between the digital images according to the healing periods were calculated on a computer. according to Visual Analogue Scale (VAS) was used to evaluate Patient comfort and pain levels.

NCT ID: NCT03918395 Completed - Hypertrophy Clinical Trials

Supplemental Protein And Resistance Training Adaptations

SPARTA
Start date: September 1, 2018
Phase: N/A
Study type: Interventional

Chronic resistance training has been shown to increase muscle cross-sectional area, volume and strength. Individuals participating in a resistance training program may wish to consume protein supplements to aid recovery and maximise adaptation. Furthermore, antioxidants have been shown to aid recovery from acute bouts of exercise. However, the effect of antioxidants combined with protein on long term-training adaptation is not fully understood. This study will combine measures of muscle size, muscle strength and function, and the underlying changes in muscle metabolism in order to assess the effect of consuming a combined protein-antioxidant supplement during a 30 session resistance training program.