Hypertension Clinical Trial
Official title:
Effect of Different Antihypertensive Treatment on Serum Uric Acid in Newly Diagnosed Hypertensive Patients
Assessment of the influence of different antihypertensive drugs on serum uric acid in newly diagnosed hypertension patients.
Status | Not yet recruiting |
Enrollment | 280 |
Est. completion date | February 2022 |
Est. primary completion date | January 2022 |
Accepts healthy volunteers | |
Gender | All |
Age group | 30 Years and older |
Eligibility | Inclusion Criteria: - All newly diagnosed hypertensive patients aged 30 years old and above will be invited to participate in this study Exclusion Criteria: 1. Patients below 30 years old. 2. Patients with kidney disease. 3. Patients who are taking medications known to increase SUA as (Thiazide and Loop diuretics, Salicylates, Cyclosporin use) or decrease the level of uric acid in the urine as (Allopurinol, Febuoxstate). |
Country | Name | City | State |
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n/a |
Lead Sponsor | Collaborator |
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Assiut University |
Shankar A, Klein R, Klein BE, Nieto FJ. The association between serum uric acid level and long-term incidence of hypertension: Population-based cohort study. J Hum Hypertens. 2006 Dec;20(12):937-45. Epub 2006 Oct 5. — View Citation
Verdecchia P, Schillaci G, Reboldi G, Santeusanio F, Porcellati C, Brunetti P. Relation between serum uric acid and risk of cardiovascular disease in essential hypertension. The PIUMA study. Hypertension. 2000 Dec;36(6):1072-8. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The effect of different antihypertensive drugs on serum uric acid in newly diagnosed hypertension. | we will measure the change of the level of serum uric acid after 6 months from the treatment of antihypertensive durgs | 6 months from baseline | |
Secondary | obesity | it will be measured by BMI (kg/m2) | 6 months from baseline |
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