Hypertension Clinical Trial
Official title:
Optimizing Linkage and Retention to Hypertension Care in Rural Kenya
Cardiovascular disease (CVD) is the leading cause of death in sub-Saharan Africa among adults
above age 30. The prevalence of hypertension, a major risk factor for CVD, is increasing over
time in sub-Saharan Africa, exerting a significant epidemiologic and economic burden on the
region. Without adequate control of hypertension, its health and economic burden will
increase drastically in the decades ahead. Well established and evidence-based interventions
to manage hypertension exist; however, treatment and control rates are low.
A critical component of hypertension management is to facilitate sustained access of affected
individuals to effective clinical services. In partnership with the Government of Kenya, the
United States Agency for International Development-Academic Model Providing Access to
Healthcare Partnership (AMPATH) is expanding its clinical scope of work in rural western
Kenya to include hypertension and other chronic diseases.
However, linking and retaining individuals with elevated blood pressure to the clinical care
program has been difficult. Thus, the overall objective of this application is to utilize a
multi-disciplinary implementation research approach to address the challenge of linking and
retaining hypertensive individuals to a hypertension management program. We aim to add to
existing knowledge on scalable and sustainable strategies for optimizing control of
hypertension and other chronic diseases in low- and middle-income countries.
Hypertension awareness, treatment, and control rates are low in most regions of the world. A
critical component of hypertension management is to facilitate sustained access of affected
individuals to effective clinical services. In partnership with the Government of Kenya, the
Academic Model Providing Access to Healthcare (AMPATH) Partnership is expanding its clinical
scope of work in rural western Kenya to include hypertension and other chronic diseases.
However, linking and retaining individuals with elevated blood pressure to the clinical care
program has been difficult. To address this challenge, we propose to develop and evaluate
innovative community-based strategies and initiatives supported by mobile technology.
The objective of this application is to utilize a multi-disciplinary implementation research
approach to address the challenge of linking and retaining hypertensive individuals to a
hypertension management program. The central hypothesis is: community health workers (CHWs),
equipped with a tailored behavioral communication strategy and a smartphone-based tool linked
to an electronic health record, can increase linkage and retention of hypertensive
individuals to a hypertension care program and thereby significantly reduce blood pressure
among these patients. We further hypothesize that these interventions will be cost-effective.
This research will generate innovative and productive solutions to the expanding global
problem of hypertension, and will add to existing knowledge on scalable and sustainable
strategies for effectively managing hypertension and other chronic diseases in low- and
middle-income countries.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Terminated |
NCT04591808 -
Efficacy and Safety of Atorvastatin + Perindopril Fixed-Dose Combination S05167 in Adult Patients With Arterial Hypertension and Dyslipidemia
|
Phase 3 | |
Recruiting |
NCT04515303 -
Digital Intervention Participation in DASH
|
||
Completed |
NCT05433233 -
Effects of Lifestyle Walking on Blood Pressure in Older Adults With Hypertension
|
N/A | |
Completed |
NCT05491642 -
A Study in Male and Female Participants (After Menopause) With Mild to Moderate High Blood Pressure to Learn How Safe the Study Treatment BAY3283142 is, How it Affects the Body and How it Moves Into, Through and Out of the Body After Taking Single and Multiple Doses
|
Phase 1 | |
Completed |
NCT03093532 -
A Hypertension Emergency Department Intervention Aimed at Decreasing Disparities
|
N/A | |
Completed |
NCT04507867 -
Effect of a NSS to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III
|
N/A | |
Completed |
NCT05529147 -
The Effects of Medication Induced Blood Pressure Reduction on Cerebral Hemodynamics in Hypertensive Frail Elderly
|
||
Recruiting |
NCT05976230 -
Special Drug Use Surveillance of Entresto Tablets (Hypertension)
|
||
Recruiting |
NCT06363097 -
Urinary Uromodulin, Dietary Sodium Intake and Ambulatory Blood Pressure in Patients With Chronic Kidney Disease
|
||
Completed |
NCT06008015 -
A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1015" and Co-administration of "BR1015-1" and "BR1015-2" Under Fed Conditions in Healthy Volunteers
|
Phase 1 | |
Completed |
NCT05387174 -
Nursing Intervention in Two Risk Factors of the Metabolic Syndrome and Quality of Life in the Climacteric Period
|
N/A | |
Completed |
NCT04082585 -
Total Health Improvement Program Research Project
|
||
Recruiting |
NCT05121337 -
Groceries for Black Residents of Boston to Stop Hypertension Among Adults Without Treated Hypertension
|
N/A | |
Withdrawn |
NCT04922424 -
Mechanisms and Interventions to Address Cardiovascular Risk of Gender-affirming Hormone Therapy in Trans Men
|
Phase 1 | |
Active, not recruiting |
NCT05062161 -
Sleep Duration and Blood Pressure During Sleep
|
N/A | |
Completed |
NCT05087290 -
LOnger-term Effects of COVID-19 INfection on Blood Vessels And Blood pRessure (LOCHINVAR)
|
||
Not yet recruiting |
NCT05038774 -
Educational Intervention for Hypertension Management
|
N/A | |
Completed |
NCT05621694 -
Exploring Oxytocin Response to Meditative Movement
|
N/A | |
Completed |
NCT05688917 -
Green Coffee Effect on Metabolic Syndrome
|
N/A | |
Recruiting |
NCT05575453 -
OPTIMA-BP: Empowering PaTients in MAnaging Blood Pressure
|
N/A |