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NCT00313430 Clinical Trial

Urinary Concentration and Diluting Ability in Patients With Chronic Renal Disease and/ or Hypertension

Hypertension Clinical Trial

Official title:
Urinary Concentration and Diluting Ability in Patients With Chronic Renal Disease or Hypertension

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00313430
Other study ID # MED. RES.HOS 2004 03/IT
Secondary ID
Status Completed
Phase N/A
First received April 11, 2006
Last updated August 19, 2015
Start date May 2004

Study information
Verified date August 2015
Source Regional Hospital Holstebro
Contact n/a
Is FDA regulated No
Health authority Denmark: Ethics Committee
Study type Observational

Clinical Trial Summary

The investigators want to test the hypothesis that patients with chronic renal disease have a poorer ability to preserve water after being thirsty and a poorer ability to excrete water after a load of fluid. They presume that these abilities become poorer when renal insufficiency progresses. The investigators further hypothesize that patients with hypertension also have a decreased ability to concentrate and dilute urine.

Recruitment information / eligibility
Status Completed
Enrollment 50
Est. completion date
Est. primary completion date March 2008
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria:

- Patients with chronic renal insufficiency, aged between 18 and 65, both men and women

- Creatinine clearance between 30-59 ml/min

- Patients with hypertension, aged between 18 and 65, both men and women; hypertension is defined as a mean arterial blood pressure in the daytime that is more than 140/90 mm Hg.

- Healthy volunteers, aged between 18 and 65, both men and women

Exclusion Criteria:

- Clinical signs or history of disease in the heart, lungs, liver, brain, and endocrine organs

- Cancer

- Alcohol abuse

- Medicine abuse

- Pregnancy

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Locations
Country Name City State
Denmark Department of Medicine, Holstebro Hospital Holstebro Ringkjoebing

Sponsors (1)
Lead Sponsor Collaborator
Erling Bjerregaard Pedersen

Country where clinical trial is conducted

Denmark, 

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