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Hypertension clinical trials

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NCT ID: NCT04953156 Completed - Hypertension Clinical Trials

Nitroglycerine Versus Dexmedetomidine Infusion in Intraoperative Management of Uncontrolled Hypertension

Start date: July 3, 2021
Phase:
Study type: Observational

This study aim to compare the efficacy of intraoperative dexmedetomidine infusion versus Nitroglycerin infusion in cancer patients with accidental uncontrolled intraoperative elevation of blood pressure.

NCT ID: NCT04952051 Completed - Hypertension Clinical Trials

Enalapril Folic Acid Tablets Combined With CCB or Diuretic to Prevent Stroke in Patients With Type H Hypertension

Start date: July 1, 2014
Phase: Phase 3
Study type: Interventional

Hypertension is a common condition that can cause serious events such as stroke, coronary heart disease and heart failure. Homocysteine (Hcy) is a substance in the body that is harmful to blood vessels. Hyperhomocysteinemia (plasma Hcy≥10 mol/L), which is associated with hypertension, significantly increases the risk of stroke. This type of high blood pressure is called type "H" hypertension. Enalapril folic acid tablet is an innovative drug developed independently in China and is the first choice for the treatment of H type hypertension. Patients with type H hypertension should be treated with enalapril folic acid tablets to reduce stroke. However, some patients had poor blood pressure control after monotherapy. At this time, other antihypertensive drugs should be used in combination. Amlodipine and Hydrochlorothiazide are the most commonly used and the best combination. The purpose of this study was to observe the difference in the efficacy of enalapril folic acid tablets in patients with uncontrolled blood pressure who were well tolerated and randomized to aminoclodipine or hydrochlorothiazide in reducing stroke and other cardiovascular and cerebrovascular events, and to explore the relationship between various alternative measures and efficacy.

NCT ID: NCT04948918 Completed - Hypertension Clinical Trials

Distal Renal Denervation to Prevent Renal Function Decline in Patients With T2DM and Hypertension

REFRAIN
Start date: September 20, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to test the hypothesis that distal renal denervation (RDN) may delay or prevent the progressive decline of renal function in patients with type 2 diabetes mellitus and hypertension

NCT ID: NCT04944472 Completed - Clinical trials for Prevention, Arterial Hypertension

Possibilities of Perceiving Information on the Primary Prevention of Cardiovascular Diseases in Persons Suffering From Essential Hypertension Through a Social Network

SocialCor
Start date: February 1, 2021
Phase:
Study type: Observational

A randomized, prospective study conducted on the basis of a social network (Instagram platform), two-stage. At the first stage, the online school "Save Your Heart" was announced and 945 applicants were enrolled in the training. The online school curriculum consisted of the following blocks: "Risk Factors for Cardiovascular Diseases (CVD)", "Healthy Nutrition for the Heart", "Cholesterol. What is important for the patient to know? "," Physical activity for the prevention of CVD "," Overweight and obesity "," Smoking as a risk factor for CVD "," AH: diagnosis "," AH: treatment "," Myocardial infarction: diagnosis and treatment". At the 2nd stage, 125 participants were selected by random randomization, then distributed into 4 training groups to provide training materials: group 1 (n = 31) - then text publications up to 4 thousand characters, group 2 (n = 31) - short video clips up to 5 minutes, group 3 (n = 33) - first text publications, then video clips, group 4 (n = 30) - video clips, then text publications. Before and after school, respondents from all four groups completed the HDKQ questionnaire.

NCT ID: NCT04944290 Completed - Ocular Hypertension Clinical Trials

To Compare the Efficacy and Safety of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes

Start date: May 28, 2021
Phase: Phase 3
Study type: Interventional

To compare the efficacy and safety of Perrigo's product to an FDA approved product in the treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Both Eyes.

NCT ID: NCT04936022 Completed - Hypertension Clinical Trials

Isometric Exercise for People With Raised Blood Pressure

IsoFIT-BP
Start date: February 1, 2020
Phase: N/A
Study type: Interventional

High blood pressure affects many people in the United Kingdom. People with raised blood pressure (140-159/90-99 mmHg) are recommended to make changes in their lifestyle (e.g. smoking/alcohol/diet/exercise) and/or medication in order to reduce their blood pressure. Current knowledge suggests that a particular type of exercise - isometric exercise - can lower blood pressure. Isometric exercise involves holding a fixed body position for a short period of time. As most of the information about the benefits of this type of exercise comes from laboratory-based studies, researchers want to find out if it is possible for GP practices to offer NHS patients with clinically high blood pressure an isometric exercise plan to do at home and how it might affect their blood pressure over 6 months. They will also find out the experiences of those doing this type of exercise and whether it can be done consistently at home over time.

NCT ID: NCT04930263 Completed - Hypertension Clinical Trials

Walking Exercise on Memory, Subjective Cognitive Complaint, and Brain-derived Neurotrophic Factor for Hypertension

Start date: November 9, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effect of 6-month aerobic walking program on memory, subjective cognitive complaints, and brain-derived neurotrophic factor for older hypertensive women. Participants will be randomly assigned to the experimental group and the control group. The intervention group will last for 24 weeks. The outcome measurements included memory, subjective cognitive complaints, and brain-derived neurotrophic factor.

NCT ID: NCT04927299 Completed - Clinical trials for Essential Arterial Hypertension

Efficacy and Safety of Losartan/Chlorthalidone vs Losartan/Hydrochlorothiazide in Essential Arterial Hypertension

Start date: June 30, 2022
Phase: Phase 3
Study type: Interventional

Phase IIIb, randomized, double-blind, prospective, multicenter study to evaluate the efficacy and safety of the fixed-dose combination of losartan / chlorthalidone compared with losartan / hydrochlorothiazide in the treatment of patients with essential arterial hypertension.

NCT ID: NCT04920825 Completed - Clinical trials for Endocrine and Metabolic Secondary Hypertension

Sacha Inchi Oil Supplementation in 3Hs

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the effect of Sacha Inchi Oil supplementation among the 3Hs patients.

NCT ID: NCT04919031 Completed - Hypertension Clinical Trials

Inspiratory Muscle Trainer and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) COVID-19 Persistent Symptoms

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

Inspiratory muscle training considered as safe and valid method to improve respiratory muscle strength and functional capacity among uncountable conditions which could improve post COVID-19 persistent symptoms including but not limited to respiratory muscle strength, diminishing dyspnea, enhance blood oxygenation, and patient's functional capacity and quality of life.