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Hypersensitivity clinical trials

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NCT ID: NCT06288503 Recruiting - Clinical trials for Cow's Milk Protein Allergy

Hydrolysed Rice Formula Study

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

This non-inferiority study aims to determine whether a hydrolysed rice protein formula is as effective as a cow's milk protein based extensively hydrolysed formula using a double-blind, randomised-controlled design over a 28-day intervention period followed by a 2-month follow-up period in infants 0-13 months of age presenting with symptoms/clinical history suggestive of cow's milk allergy. The primary outcome is growth, and secondary outcomes are gastrointestinal tolerance, and differences in intake, allergic symptoms, parental QOL, acceptability, dietary intake, and safety.

NCT ID: NCT06287060 Not yet recruiting - Clinical trials for Bleaching Effect and Postoperative Sensitivity of Strawberry Extract

Bleaching Effect of Strawberry Extract Versus Hydrogen Peroxide in Patients With Extrinsic Staining

Start date: July 2024
Phase: N/A
Study type: Interventional

with limited evidence based information in literature about using Strawberry extract for teeth bleaching in patients with extrinsic staining , it is beneficial to evaluate this new material using a randomized controlled clinical trial to test the null hypothesis that this extract will have the same effect as Hydrogen peroxide regarding the bleaching effect and hypersensitivity.

NCT ID: NCT06283537 Not yet recruiting - Clinical trials for Training Group, Sensitivity

Online Episiotomy Simulation Training for Midwifery Students

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

Purpose: To determine the effect of online episiotomy simulation training to midwifery students on their episiotomy application skills, satisfaction with the teaching method and self-confidence. Method: This study is a randomized controlled experimental study. It will be conducted with third-year students studying at Kastamonu University Midwifery Department in the 2023-2024 period. In the research, all third-year students in the midwifery department (n=60) will be divided into 30 students into the online education group and 30 students into the face-to-face education group using a random sampling model. "Student Information Form", "Episiotomy Skill Evaluation Form" and "Student Satisfaction and Self-Confidence in Learning Scale" will be used to collect data.

NCT ID: NCT06276777 Not yet recruiting - Clinical trials for Dentin Hypersensitivity

The Effect of Using Desensitizers Containing S-PRG In Treatment Of Dentin Hypersensitivity Over 6 Months: A Randomized Clinical Trial

S-PRG
Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the effect of desensitizer containing S-PRG have similar effect as sodium fluoride with functionalized tri-calcium phosphate containing desensitizer in relieving dentinal hypersensitivity in adult patients for six months follow-up. patients will be asked to report pain degree on the visual analogue scale (VAS) along the follow up periods on both groups.

NCT ID: NCT06273930 Recruiting - Sensitivity, Tooth Clinical Trials

Reduction of Dentine Hypersensitivity After Use of Different Dentifrices

Dentrifices
Start date: February 1, 2024
Phase: Phase 1
Study type: Interventional

To assess the impact of the use of 5% Calcium Sodium Phosphosilicate or 8% Arginine dentifrices on dentinal hypersensitivity following non-surgical periodontal therapy in patients with periodontitis.

NCT ID: NCT06273605 Recruiting - Food Allergy Clinical Trials

The Egg Up Trial - Testing a New Treatment Pathway for Infants With Newly Diagnosed Egg Allergy

Start date: April 9, 2024
Phase: N/A
Study type: Interventional

The goal of this study is to test the safety and feasibility of a change in management approach for infants with newly diagnosed egg allergy. Infants with newly diagnosed egg allergy will have egg introduced via a gradual and graded home based approach known as an "egg ladder" supervised by a dietitian. The main questions this study aims to answer are how safe and feasible are home-based dietitian-led "egg ladders" as a treatment pathway to achieve tolerance of egg for newly diagnosed infants with egg allergy.

NCT ID: NCT06273371 Completed - Clinical trials for Cow's Milk Protein Allergy

Tolerance and Growth Outcomes in Children Diagnosed With Cow's Milk Protein Allergy and Prescribed an Extensively Hydrolyzed Casein Formula (Damira 2000©) in Spain

DELISA
Start date: December 12, 2023
Phase:
Study type: Observational

Damira 2000© is a 100% extensive casein hydrolysate (eHCF). It is formulated to help reverse growth retardation as a result of cow's milk proteins allergy (CMPA), to be well tolerated and to help improve symptoms.Damira 2000 is indicated for allergy/intolerance to cow's milk proteins, atopic dermatitis secondary to CMPA, intestinal malabsorption processes and prevention of allergy/intolerance to cow's milk proteins.The study aimed at evaluating the tolerance of Damira 2000 in a cohort of children with CMPA.

NCT ID: NCT06272370 Recruiting - Asthma Clinical Trials

Individualizing Treatment for Asthma in Primary Care

iTREAT-PC
Start date: February 1, 2024
Phase: Phase 4
Study type: Interventional

This is a patient level randomized trial for teenagers and adults with asthma who will be randomized to four arms - enhance usual care, rescue inhaled corticosteroids, azithromycin and both rescue inhaled corticosteroids and azithromycin. Participants in all arms will be offered access to an online asthma symptom monitoring system.

NCT ID: NCT06271993 Recruiting - Clinical trials for Allergic Skin Reaction

SPT for Sensitization of Collagen Dressing

Start date: February 8, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to determine the sensitization (contact allergy) potential of the test product ColActive Plus Collagen Matrix Dressing after a skin prick test on the skin of healthy human subjects. The main question it aims to answer is: • Does the product induce any sensitization (contact allergy) after a skin prick using a UniTest PC (pain control) device in healthy human subjects? Participants will have the test product and both positive and negative controls applied, and skin response will be evaluated by an allergist at 15 minutes, 6 hours, and 24-48 hours post-application to see if sensitization occurs.

NCT ID: NCT06264648 Completed - Clinical trials for Sensitivity Training Groups

Investigation of Palpation Pressure Sensitivity

Start date: May 3, 2023
Phase: N/A
Study type: Interventional

The study is planned for searching physiotherapists palpation abilities. There were 2 groups of physiotherapists. They were asked for to push target pressures. After making some exercise, the assesment was done again.