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Hyperplasia clinical trials

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NCT ID: NCT06157164 Recruiting - Clinical trials for Benign Prostatic Hyperplasia

IIT-2022-Simultaneous Urolift™ and Median Lobe Enucleation

Start date: February 6, 2023
Phase:
Study type: Observational

To evaluate postoperative outcomes of BPH/Lower urinary tract symptoms, erectile function, and ejaculatory capacity of simultaneous UroLiftTM and Holmium laser enucleation of the prostatic median lobe.

NCT ID: NCT06136819 Recruiting - Clinical trials for Lower Urinary Tract Symptoms

RT-310 Dose Escalation BPH Study

Start date: April 19, 2024
Phase: Phase 1
Study type: Interventional

RT-310, a novel implant, is intended to minimally invasive treat locally the prostate gland for the management of prostate disease, while minimizing side-effects. The objectives of the study are to assess whether RT-310 is safe and feasible for the participant population.

NCT ID: NCT06116851 Recruiting - Prostate Cancer Clinical Trials

Prostate Metabolism, Cancer Risk and Gut Microbiota

PROMIC
Start date: June 1, 2022
Phase:
Study type: Observational

This is a prospective, single center translational multiple cohort study to investigate the association of gut microbiota and prostate cancer.

NCT ID: NCT06102863 Recruiting - Clinical trials for Atypical Endometrial Hyperplasia and Endometrial Carcinoma Stage I

Progesterone Therapeutic Regimen Plus Statins in Young Women With Early Endometrial Carcinoma and Atypical Endometrial Hyperplasia

Start date: April 1, 2023
Phase: Phase 2
Study type: Interventional

To explore the treatment efficacy of Progesterone Therapeutic Regimen Plus Statins in patients with atypical endometrial hyperplasia (AEH) and early endometrial carcinoma (EEC) for conservative treatment.

NCT ID: NCT06091618 Recruiting - Clinical trials for Prostatic Hyperplasia

Laser Vaporization of the Prostate: Comparing Between Ejaculatory Preserving and Non-ejaculatory Preserving Technique

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

The present work aimed to compare between The Outcomes of conventional technique of laser prostatectomy versus the new ejaculatory sparing technique .

NCT ID: NCT06090617 Recruiting - Hypertension Clinical Trials

Water and Electrolytes Content in HYpertension (WHYSKI) in the SKIn

WHYSKI
Start date: January 1, 2021
Phase:
Study type: Observational

WHYSKI is a prospective within-patient observational clinical study designed to test the hypothesis that alterations of Na+, K+, water, and the lympho-angiogenetic transcription factor Tonicity Enhancing Binding Protein (TonEBP) mRNA take place in the interstitium of the skin compartment of patients with arterial hypertension due to primary aldosteronism in whom hypertension can be surgically cured.

NCT ID: NCT06071845 Recruiting - Barrett Esophagus Clinical Trials

Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples

SOS4C
Start date: October 16, 2023
Phase: N/A
Study type: Interventional

This clinical trial evaluates the use of cytosponge, a minimally invasive collection device, for the detection of Barrett's esophagus (BE) in patients undergoing endoscopy. Non-endoscopic swallowable encapsulate sponge cell collection devices combined with markers for BE/esophageal adenocarcinoma (EAC) detection are a guideline-endorsed alternative to endoscopy for BE screening. The Oncoguard registered trademark Esophagus test (OGE) test uses esophageal cytology specimens collected with a minimally invasive, non-endoscopic, encapsulated sponge sampling device to identify BE/EAC biomarkers that indicate whether a patient should undergo diagnostic endoscopy. The OGE test is a simple and cost effective screening method that may lower barriers to widespread adoption of BE screening in at risk patients, resulting in increased and earlier detection of BE/EAC.

NCT ID: NCT06062875 Recruiting - Clinical trials for Benign Prostatic Hyperplasia (BPH)

Effects of TNF Blockade on Human BPH/LUTS

Start date: January 24, 2024
Phase: Phase 2
Study type: Interventional

Specific Aim 1. To evaluate the efficacy of TNF antagonist action in BPH/LUTS Specific Aim 2. Define the consequences of TNF antagonist therapy on prostate tissue Specific Aim 3. Identify genetic predictors to stratify patients with differential response to TNF-antagonist therapy.

NCT ID: NCT06051942 Recruiting - Clinical trials for Benign Prostatic Hyperplasia

PRCT001 Aquablation theraPy Outcomes in pRostate Cancer patienTs

Start date: November 22, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to assess the performance and safety of the AQUABEAM Robotic System for the resection and removal of prostate tissue in patients experiencing lower urinary tract symptoms (LUTS) and are diagnosed with localized prostate cancer. Participants will go through baseline and follow up assessments up to 12 months.

NCT ID: NCT06050057 Recruiting - Pheochromocytoma Clinical Trials

Surgical Treatment of Adrenal Diseases- Laparoscopic vs. Robotic-assisted Adrenalectomy

Start date: September 3, 2023
Phase:
Study type: Observational

The goal of this multicenter, observational, analytic, randomized clinical trial is to analyze the laparoscopic and robot-assisted method in the surgical treatment of patients with adrenal diseases. The main question it aims to answer are: 1. to find the superiority of one the the surgical method mentioned above 2. to compare the quality of life in patients with adrenal mass before surgery and after laparoscopic or robotic-assisted adrenalectomy.