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Hyperlipidemias clinical trials

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NCT ID: NCT04672278 Completed - Hypertension Clinical Trials

Lipid-Lowering Effect and Hypotensive Effect of Shanzha Fruit Drink in Patients

Start date: January 2, 2019
Phase: N/A
Study type: Interventional

This is a single-center, randomized, double-blind, placebo-controlled, cross-over study. Subjects who meet the inclusion/exclusion criteria will be randomly and alternatively assigned to receive Shanzha fruit drink or placebo drink in the first 2 months or the last two months of the 5 months study period. In between the first and second treatment period, all patients will enter a Washout Period of 4 weeks and during which time patients should not receive any of the study functional fruit drink.

NCT ID: NCT04640012 Completed - Hyperlipidemia Clinical Trials

Ascending-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics of DC371739 Single-Dose Treatment in Healthy Subjects

Start date: September 25, 2020
Phase: Phase 1
Study type: Interventional

This study is to evaluate the safety, tolerability, pharmacokinetics of DC371739 after a single-dose oral administration in healthy Chinese subjects, and to explore the maximum tolerated dose, also the pharmacokinetics of urine and feces.

NCT ID: NCT04606602 Completed - Dyslipidemias Clinical Trials

Study to Investigate Safety, Tolerability, PK and PD Response of SLN360 in Subjects With Elevated Lipoprotein(a)

Start date: November 18, 2020
Phase: Phase 1
Study type: Interventional

This study will investigate the safety and tolerability of SLN360 in patients with elevated Lp(a).

NCT ID: NCT04573218 Completed - Clinical trials for Hypercholesterolemia

Supplementation of Oil Palm Phenolics to Improve Lipid Profile in Subjects With Minor Hyperlipidaemia

Start date: October 18, 2021
Phase: Phase 2
Study type: Interventional

An unpublished study by the investigators on healthy participants has shown that the supplementation of oil palm phenolics (OPP) at 250 mg is the optimum dose to demonstrate the ability to lower total and LDL cholesterol. There is no clinical evidence as yet on that optimum dosage of OPP supplementation in improving fasting lipid profile in minor hyperlipidemia subjects. The investigators hypothesize that in a clinical study, OPP supplemented to the minor hyperlipidemic participants will elicit a reduction in total and LDL cholesterol while maintaining safety and tolerability. OPP may have the potential to be positioned as natural health supplement in improving lipid profile.

NCT ID: NCT04564352 Completed - Hyperlipidemias Clinical Trials

Hypolipidemic Effect of Adansonia Digitata

AD
Start date: January 1, 2020
Phase:
Study type: Observational

Adansonia digitata L. (AD) also known as Baobab is a huge tree that grows in many countries in sub-Saharan Africa. Many studies talking about AD biological activity including hypolipidemic, antioxidant and antimicrobials in animal's but not in human, This study will be undertaken to examine the effect of AD juice consumption against lipid profiles in traditional users and blood samples will be collected form participant's for investigated of lipid profiles pre and post AD juice drinking and the results will be compared.

NCT ID: NCT04516291 Completed - Dyslipidemias Clinical Trials

A Dose-Ranging Study With Vupanorsen (TRANSLATE-TIMI 70)

Start date: September 28, 2020
Phase: Phase 2
Study type: Interventional

This is a multicenter, Phase 2b, double-blind, placebo-controlled, parallel group study to provide data on efficacy, safety, tolerability, and pharmacokinetics (PK) of PF-07285557 (hereafter, vupanorsen) administered subcutaneously (SC) at various doses and regimens in participants with dyslipidemia, defined in this study as participants with elevated non-HDL-C and TG who are receiving a stable dose of a statin. This study is also known as TaRgeting ANGPTL3 with an aNtiSense oLigonucleotide in AdulTs with dyslipidEmia (TRANSLATE-TIMI 70).

NCT ID: NCT04469673 Completed - Hyperlipemia Clinical Trials

A Study to Evaluate the Safety, Tolerability and Efficacy of Multiple Doses of JS002 in Patients With Hyperlipidemia..

Start date: May 23, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

JS002 is a recombinant humanized anti-PCSK9 monoclonal antibody.

NCT ID: NCT04457024 Completed - Hyperlipidemia Clinical Trials

Tennis Elbow Patients Undergoing Closed Therapy Can Easily Cause Tendon Tear

Start date: January 1, 2020
Phase:
Study type: Observational [Patient Registry]

To explore whether there is a difference in the rate of tendon tear after hyperlipemia in tennis elbow patients and those with normal blood lipids after closed treatment, which provides clues for further exploration of its mechanism. 1. Collect data from 108 cases of tennis elbow patients treated at the Institute of Sports Medicine, Peking University Third Hospital from January 2010 to December 2018 at the Institute of Sports Medicine, Peking University Third Hospital. Statistics included the sex, age, BMI, number of closures, total cholesterol, triglycerides, low-density lipoprotein, high-density lipoprotein. 2. Retrieve the MRI imaging data of the above-mentioned patients, and use the extensor tendon at the humerus to see if there is a tear as an observation indicator. Analyze the difference of tendon tear after closed treatment in patients with high blood fat and normal blood fat.

NCT ID: NCT04394715 Completed - Clinical trials for High Risk Atherosclerotic Cardiovascular Disease

Pragmatic Trial of Messaging to Providers About Treatment of Hyperlipidemia (PROMPT-LIPID)

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

This study is designed to evaluate the efficacy of automated electronic alerts in the electronic health record to improve rates of best practices in the treatment of patients with hyperlipidemia who present in the setting of outpatient primary care and family medicine practices within the Yale New Haven Health System.

NCT ID: NCT04382521 Completed - Hypertension Clinical Trials

A Text Message Intervention to Promote Health Behaviors in Cardiac Risk Conditions

Start date: September 22, 2020
Phase: N/A
Study type: Interventional

This is a randomized pilot trial to examine the feasibility, acceptability, and preliminary efficacy of an adaptive text message intervention (TMI) to promote well-being and health behavior adherence in 60 patients with two or more cardiac risk conditions (hypertension, type 2 diabetes, or hyperlipidemia).