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Hyperlipidemia clinical trials

View clinical trials related to Hyperlipidemia.

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NCT ID: NCT01380730 Completed - Hyperlipidemia Clinical Trials

LAPLACE-TIMI 57: Low-density Lipoprotein Cholesterol (LDL-C) Assessment With PCSK9 monoclonaL Antibody Inhibition Combined With Statin thErapy

LAPLACE
Start date: July 1, 2011
Phase: Phase 2
Study type: Interventional

To evaluate the effect of 12 weeks of subcutaneous (SC) evolocumab (AMG 145) administered every 2 weeks (Q2W) or every 4 weeks (Q4W), compared with placebo, on percent change from baseline in LDL-C when used in addition to a statin in adults with hypercholesterolemia.

NCT ID: NCT01377064 Completed - Obesity Clinical Trials

Home-based Exercise for Management of HIV-associated Cardiovascular Disease Risk

Start date: March 2011
Phase: Phase 1
Study type: Interventional

Because of advances in drug treatment, people living with HIV/AIDS (PLWHA) are living longer, but are also at greater risk for cardiovascular disease (CVD) and diabetes. Exercise and increased physical activity can reduce the risk factors for these diseases in PLWHA, but no studies have tested an at-home exercise program that would benefit low income people and others who do not have access to exercise facilities. This study will test the feasibility of an at-home exercise program for PLWHA and prepare for a full-scale intervention study, which may lead to a reduction in CVD risk among PLWHA.

NCT ID: NCT01375777 Completed - Hyperlipidemia Clinical Trials

Monoclonal Antibody Against PCSK9 to Reduce Elevated Low-density Lipoprotein Cholesterol (LDL-C) in Adults Currently Not Receiving Drug Therapy for Easing Lipid Levels

MENDEL
Start date: July 6, 2011
Phase: Phase 2
Study type: Interventional

The primary objective was to evaluate the effect of 12 weeks of subcutaneous evolocumab (AMG 145) every 2 weeks (Q2W) or every 4 weeks (Q4W), compared with placebo, on the percent change from baseline in LDL-C when used as monotherapy in adults with hypercholesterolemia.

NCT ID: NCT01375764 Completed - Hyperlipidemia Clinical Trials

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects

GAUSS
Start date: July 28, 2011
Phase: Phase 2
Study type: Interventional

The primary objective was to evaluate the effect of 12 weeks of subcutaneous evolocumab (AMG 145), compared with ezetimibe, on percent change from baseline in low-density lipoprotein cholesterol (LDL-C) in patients with hypercholesterolemia unable to tolerate an effective dose of a statin.

NCT ID: NCT01360567 Completed - Type 2 Diabetes Clinical Trials

The Effect of Green Tea Extract on Type 2 Diabetes With Hyperlipidemia

Start date: May 2011
Phase: Phase 3
Study type: Interventional

The aim of the study is to examine whether the extract of green tea is effective on type 2 diabetes and hyperlipidemia.

NCT ID: NCT01353404 Completed - Hyperlipidemia Clinical Trials

Relative Bioavailability Study of Lipidil® Supra (Fenofibrate 160mg) Versus SYO-0805 (Fenofibrate 65mg)

Start date: June 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the bioequivalence of Lipidil® Supra (fenofibrate 160mg) versus SYO-0805 (fenofibrate 65mg) in single dose oral administration.

NCT ID: NCT01349010 Completed - Hyperlipidemia Clinical Trials

Efficacy and Safety of Imported Probucol to Treat Hyperlipidemia

Start date: April 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of imported Probucol in hyperlipidemia patients.

NCT ID: NCT01332747 Completed - Hyperlipidemia Clinical Trials

Clinical Study to Evaluate Antihyperlipidemic Effect of a Classical Unani Antiobesity Formulation

Start date: May 2010
Phase: Phase 2
Study type: Interventional

The purpose of this clinical trial is to study the comparative effect of a classical unani antiobesity drug safoof-e-muhazzil on hyperlipidemia in its classical powder form and in compressed tablet form against a standard control.

NCT ID: NCT01327014 Completed - Hyperlipidemia Clinical Trials

Efficacy and Safety Study of Lipid-Lowering Effects of XueZhiKang (XZK) in Patients With Hyperlipidemia

Start date: April 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to demonstrate the efficacy of XueZhiKang to improve plasma lipid profile, as compared to placebo, in outpatients with hyperlipidemia.

NCT ID: NCT01326442 Completed - Obesity Clinical Trials

Vitamin D and Omega-3 Inhibit Metabolic Syndrome

Start date: April 2011
Phase: Phase 3
Study type: Interventional

The study will test the hypothesis that supplementing the diet of subjects with Metabolic Syndrome with 2000 IU vitamin D and 1.8 g omega-3 fatty acids (EPA + DHA) per day, will facilitate weight loss, improve body composition and reduce metabolic and biochemical risk factors associated with type II diabetes and cardiovascular disease. Adult men and women who meet the International Diabetes Federation criteria for Metabolic Syndrome will be enrolled and embark on a 16 week diet and exercise intervention using a low glycemic index diet with or without the supplementary vitamin D and omega-3. Subjects will be counseled weekly and blood collected at weeks 0 and 16.