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Hyperkinesis clinical trials

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NCT ID: NCT06438419 Not yet recruiting - Parkinson Disease Clinical Trials

Parkinsonism-Related Oscillations in the Cortico-Basal Ganglia-Thalamic Network During Movement: Beyond the Frequency Range

MOVOSCILLCBGT
Start date: June 2024
Phase: N/A
Study type: Interventional

Expression of hypokinetic and hyperkinetic motor symptoms in Parkinson's disease (PD) is associated with pathological synchronous oscillations of neuronal activity (local field potential/LFP) in the cortico-subcortical network with a wide frequency range. In the present project, we propose to study cortico-subcortical oscillations and their synchronization in patients operated for PD (subthalamic deep brain stimulation (STN-DBS)) during distinct pharmacological and stimulation conditions (hypokinetic and hyperkinetic), using a simple motor task.

NCT ID: NCT06434831 Not yet recruiting - Clinical trials for Sacral Neuromodulation

Evaluation of Autonomic Nervous System Changes in Response to Stimulation by Sacral Neuromodulation

ESTIME
Start date: July 2, 2024
Phase: N/A
Study type: Interventional

Overactive bladder syndrome (OAB) is defined by urgent and frequent urges to urinate associated with frequent night-time urination and sometimes urinary incontinence. Sacral neuromodulation (SNM) is now one of the second-line treatments for OAB. The mode of action of SNM is still poorly understood but a number of data from recent scientific literature suggest that SNM may act, among other things, by altering the balance of the autonomic nervous system (ANS) - located at the interface between the urinary tract and the brain structures regulating the functioning of the urinary tract. The aim of this study would therefore be to develop a predictive tool for the effectiveness of SNM.

NCT ID: NCT06388694 Not yet recruiting - Clinical trials for Attention-deficit Hyperactivity

Pharmacist Management of Attention Deficit Hyperactivity Disorder Medication Refill Requests

Start date: May 2, 2024
Phase: N/A
Study type: Interventional

This cluster randomized trial will compare pharmacist management of secure message requests for refills of attention deficit hyperactivity medications with primary care physician management regarding quality of care, timeliness of service, and parent care experience.

NCT ID: NCT06376331 Not yet recruiting - Clinical trials for Attention-deficit/Hyperactivity Disorder

Washed Microbiota Transplantation for Attention-deficit/Hyperactivity Disorder

Start date: April 20, 2024
Phase: Phase 1
Study type: Interventional

Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by inattention and hyperactivity-impulsivity. ADHD is often accompanied by oppositional defiant disorder and sleep disturbance, and can increase the risk of other psychiatric disorders, functional impairment in academic and occupational performance. Recently, gut microbiota has been implicated in the ADHD via gut-brain axis. In this study, investigators aimed to evaluate the efficacy of WMT for core ADHD symptoms and its comorbidities using specialized questionnaires for ADHD and investigate the underlying mechanism.

NCT ID: NCT06348121 Not yet recruiting - Clinical trials for Attention Deficit Hyperactivity Disorder

Impact of Probiotics on Children With ADHD

Start date: May 7, 2024
Phase: N/A
Study type: Interventional

To evaluate the efficacy and safety of probiotic product WecProB as food supplements for the treatment of clinical symptoms in children with ADHD, in comparison with placebo.

NCT ID: NCT06277440 Not yet recruiting - Clinical trials for Developmental Delays

Cognitive Training for Attention Deficit Hyperactivity Disorder and Developmental Delays

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

To explore whether children with Attention Deficit Hyperactivity Disorder and developmental delays who receive cognitive training and conventional rehabilitation can improve executive function more than traditional rehabilitation alone. A magnetoencephalographic examination will be arranged to explore how brain network activation works. Research method: 20 preschool children with Attention Deficit Hyperactivity Disorder and developmental delays under rehabilitation therapy will be collected. They will be randomly assigned to the experimental group (receiving rehabilitation therapy and three times per week for 15 minutes, a total of 12 weeks of interactive cognitive training) and the control group (receiving rehabilitation therapy only). Therapeutic effects will be evaluated.

NCT ID: NCT06248229 Not yet recruiting - Fatigue Clinical Trials

A Trial of Dyanavel XR in Treating Co-occurring Fatigue Symptoms in Adults With Attention Deficit Hyperactivity Disorder (ADHD).

Start date: May 1, 2024
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to study the impact of Dyanavel on co-occuring fatigue in adults with Attention Deficit/Hyperactivity Disorder. The main question it aims to answer is whether Dyanavel XR leads to a statistically significant reduction in fatigue compared to placebo, as measured by the Fatigue Symptom Inventory.

NCT ID: NCT06232226 Not yet recruiting - Clinical trials for Attention Deficit Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

ADA
Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The ADA cohort aims for the systematic and standardized collection of sociodemographic, clinical and neuropsychological data, during 2 visits (inclusion and 12 months), from patients suffering from the co-occurrence of ADHD (Attention Deficit Hyperactivity Disorder) and addiction(s), in addition to the treatment as usual adapted to each situation.

NCT ID: NCT06140979 Not yet recruiting - Clinical trials for Attention Deficit Hyperactivity Disorder

Visual Focused Play Intervention for Children With ADHD

Start date: November 10, 2023
Phase: N/A
Study type: Interventional

This is a single-center, randomized, double-blind, sham-controlled study that will recruit children with attention deficit hyperactivity disorder and randomly assign them to a test group and a control group. The patients in the test group will be given a visual focus game to play and the patients in the control group will be given an animated video of the game that had no therapeutic effect. Treatment will be required at least 5 times per week for 2 weeks, with each game or video session lasting 30 minutes. Clinical scales and functional near-infrared spectroscopic imaging will be performed before and at the end of the 2 weeks of treatment, respectively.

NCT ID: NCT06115603 Not yet recruiting - Clinical trials for Attention-Deficit/Hyperactivity Disorder

The Effects of Cannabigerol on Attention-Deficit/Hyperactivity Disorder

CBG
Start date: January 2024
Phase: Phase 2
Study type: Interventional

The goal of this clinical trial is to evaluate the effects of Cannabigerol (CBG) on symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in a sample of participants with ADHD. The main question it aims to answer is: Does CBG reduce ADHD symptoms relative to placebo? Participants will complete two weeks of product administration for each condition (placebo or 80mg CBG daily), separated by a one-week washout period. Daily and weekly surveys will be administered to monitor effects.