Postprandial Response to Different Jams

Hyperglycemia, Postprandial Clinical Trial

Official title:

Study of the Effects of Three Strawberry Jams, Differing in Carbohydrate and Antioxidant Content, on Postprandial Response in Healthy Subjects

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01684332
• Other study ID #: UNAV-078-2010
• Status: Completed
• Phase: N/A
• First received: September 10, 2012
• Last updated: September 18, 2012
• Start date: September 2010
• Est. completion date: March 2011

Study information

• Verified date: September 2012
• Source: Clinica Universidad de Navarra, Universidad de Navarra
• Contact: n/a
• Is FDA regulated: No
• Health authority: Spain: Comité Ético de Investigación Clínica
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to investigate the effects of an acute intake of three different types of strawberry jam, differing in the carbohydrates and antioxidants content, on postprandial glucose metabolism, lipid profile, antioxidant status and satiety indices, in healthy adults.

Description:

Study Design: Randomized, postprandial, crossover, double-blind intervention with three arms.

Subjects: Sixteen healthy adults

Product studied: At each arm, participants consume 60g of strawberry jam:

• High-sugar jam (traditional; HS),

• Low-sugar jam (without added-sugar; LS),

• Low-sugar jam including antioxidant extract from strawberry pulp (LSA).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 16
• Est. completion date: March 2011
• Est. primary completion date: December 2010
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• Adult men and women

• Normal weight or overweight (BMI between 18.5 and 29.9 kg/m2)

• Age between 20 and 50 years old.

Exclusion Criteria:

• To suffer from any chronic disease related to metabolism,

• To follow concomitant medications,

• To follow slimming treatments or hormone replacement therapy,

• To have any inability to perform the follow-up,

• Smoking,

• Known food allergies,

• Pregnancy, lactation or menopause

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Prevention

Related Conditions & MeSH terms

• Antioxidant
• Feeding Behaviors
• Hyperglycemia
• Hyperglycemia, Postprandial
• Lipid Profile
• Postprandial

Intervention

Other:
• Strawberry Jam

Locations

Country	Name	City	State
Spain	Department of Nutrition, Food Science and Physiology	Pamplona	Navarra

Sponsors (1)

Lead Sponsor	Collaborator
Clinica Universidad de Navarra, Universidad de Navarra

Country where clinical trial is conducted

Spain, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Plasma malondialdehyde (MDA) postprandial measure	Plasma MDA measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam	up to 120 minutes	No
Secondary	Serum glucose postprandial concentration	Serum Glucose measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam	Baseline, 30, 60, 90 and 120 minutes	No
Secondary	Serum insulin postprandial concentration	Serum insulin measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam	baseline, 30, 60, 90 and 120 minutes	No
Secondary	HOMA insulin resistance index	HOMA-IR calculated at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam	Baseline, 30, 60, 90 and 120 minutes	No
Secondary	Serum total cholesterol postprandial concentration	Serum total cholesterol measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam	Baseline, 30, 60, 90 and 120 minutes	No
Secondary	Serum HDL-cholesterol postprandial concentration	Serum HDL-cholesterol measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam	Baseline, 30, 60, 90 and 120 minutes	No
Secondary	Serum LDL-cholesterol postprandial concentration	Serum LDL-cholesterol calculated at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam	Baseline, 30, 60, 90 and 120 minutes	No
Secondary	Serum Uric Acid postprandial concentration	Serum Uric Acid measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam	Baseline, 30, 60, 90 and 120 minutes	No
Secondary	Plasma Glutathione Peroxidase postprandial activity	Plasma Glutathione Peroxidase activity measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam	Baseline, 30, 60, 90 and 120 minutes	No
Secondary	Postprandial Plasma Total Antioxidant Capacity	Plasma Total Antioxidant capacity measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam	Baseline, 30, 60, 90 and 120 minutes	No

External Links

•   University of Navarra