Pain Response to Cannabidiol in Induced Acute Nociceptive Pain, Allodynia and Hyperalgesia By Using a Model Mimicking Acute Pain in Healthy Adults — CANAB I  

Hyperalgesia Clinical Trial

Official title: Pain Response to Cannabidiol in Induced Acute Nociceptive Pain, Allodynia and Hyperalgesia By Using a Model Mimicking Acute Pain in Healthy Adults

Status Completed

Clinical Trial Summary

This study is to investigate the effect of CBD on acute pain in healthy volunteers in a well-established acute pain model.

Clinical Trial Description

There are no studies investigating Cannabidiol (CBD) in an acute pain model in human beings. This is however of great clinical value because:

1. Patients are often treated insufficiently with the commonly used analgesics in acute pain therapy or the available selection of analgesics is limited by their contraindications and side-effects.

2. CBD could be an option to optimize pain therapy if the pain relief is not satisfactory.

3. CBD in contrast to ∆9-tetrahydrocannabinol (THC) has only few side effects and due to a possible dose reduction of other analgesics patients might benefit from a better side-effect profile.

This study is to investigate the effect of CBD on acute pain in healthy volunteers in a well-established acute pain model. ;

Related Conditions & MeSH terms

• Acute Pain
• Allodynia
• Hyperalgesia
• Nociceptive Pain
• Pain Sensation

• NCT number: NCT03985995
• Study type: Interventional
• Source: University Hospital, Basel, Switzerland
• Status: Completed
• Phase: N/A
• Start date: September 16, 2019
• Completion date: December 23, 2019