Hyperalgesia Clinical Trial
Despite improvements in analgesic treatment following total knee arthroplasty (TKA) for
osteoarthrosis, a substantial part of patients still have severe acute pain after surgery.
It has been suggested that preoperative degree of intraarticular inflammation is associated
to postoperative degree of pain and level of function. Furthermore it is known, that
patients with preoperative inflammation have hyperalgesia and severe movement related pain.
The aim of this study is to investigate the effect of a preoperative intraarticular
injection of Methylprednisoloneacetate in reducing acute postoperative pain after total knee
arthroplasty in patients with signs of severe pre-operative inflammation and pain.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
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