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Hydrocephalus clinical trials

View clinical trials related to Hydrocephalus.

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NCT ID: NCT04450797 Recruiting - Hydrocephalus Clinical Trials

Intraoperative Ultrasound Guided Compared to Stereotactic Navigated Ventriculoperitoneal Shunt Placement

NaVPS
Start date: February 26, 2020
Phase: N/A
Study type: Interventional

This study is to prospectively compare Ultrasound guided (US-G) Ventriculoperitoneal Shunt (VPS) placement to stereotactic navigation in a randomized controlled fashion with the surgical intervention time as primary outcome. All patients entering the University Hospital of Basel for elective or emergent VPS surgery will be randomized in 1:1 fashion to one of the study groups at admission or the day before the operation.

NCT ID: NCT04436068 Recruiting - Hydrocephalus Clinical Trials

Hyperfine Portable MRI in Hydrocephalus and Other Conditions Prompting Outpatient Brain Imaging

Start date: June 28, 2019
Phase: N/A
Study type: Interventional

Participants with known or suspected hydrocephalus will receive brain scans using the Hyperfine, low field strength, portable, magnetic resonance imaging (MRI) system in addition to their scheduled outpatient standard of care clinical computed tomography (CT) or MRI scan. The purpose of this pilot study is to evaluate the feasibility and acceptability of using the Hyperfine system in an outpatient setting and to compare its diagnostic performance to standard clinical imaging. Outpatients with other known or suspected neurological disorders or conditions prompting routine clinical brain imaging with MRI or CT will also be enrolled and the diagnostic performance of low field scans compared to that of the same day standard of care clinical imaging.

NCT ID: NCT04434053 Recruiting - Clinical trials for Normal Pressure Hydrocephalus

Adjustable Gravitational vs. Adjustable Differential Pressure Valves in iNPH

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

The goal of the study is to verify theoretical benefit of ventriculoperitoneal shunting with MIETHKE M.blue® valve in patients with iNPH. The study is designed to assess walking and balance, urinary function, cognitive performance and quality of life before and after shunting and compare the results between the patients with MIETHKE M.blue® and MIETHKE proGAV 2.0® (with SA 2.0®) valves.

NCT ID: NCT04363658 Recruiting - Hydrocephalus Clinical Trials

Efficacy Study of Hydrocephalus Surgery by Methods of Neuroelectrophysiology

Start date: May 10, 2020
Phase:
Study type: Observational

The symptoms of hydrocephalus containing consciousness condition with muscle tone in some patients will be relieved, after the cerebrospinal fluid release test is carried out. Neuroelectrophysiology in patients with disorders of consciousness of post-traumatic hydrocephalus (PTH) can establish the association with consciousness and muscle tone to a certain extent, and predict the shunt effect of PTH with disorders of consciousness.

NCT ID: NCT04309487 Recruiting - Clinical trials for Hydrocephalus, Normal Pressure

Diagnostic Accuracy of ShuntCheck Compared to Radionuclide Shunt: Patency in Patients With Normal Pressure Hydrocephalus

Start date: January 24, 2020
Phase:
Study type: Observational

The purpose of this study is to assess the diagnostic accuracy of ShuntCheck compared with radionuclide shunt patency testing (SPS) to detect CSF shunt flow of NPH patients with suspected shunt obstruction.

NCT ID: NCT04229693 Recruiting - Clinical trials for Hydrocephalus in Infants

Cerebrospinal Fluid Proteom in Dependence of Intranasal Breast Milk

NAMU
Start date: February 7, 2020
Phase:
Study type: Observational

Investigation of the cerebrospinal fluid proteom in preterm infants with posthemorrhagic hydrocephalus in our neonatology center with analysis for modulation of proteom in dependence of breastmilk feeding and way of application such as via gavage tube, oral or nasal application.

NCT ID: NCT04189172 Recruiting - Hydrocephalus Clinical Trials

MiDura-Study (Neuro-Patch in Duraplasty)

MiDura
Start date: February 6, 2020
Phase:
Study type: Observational

The aim of this study is to collect systematically and proactively data regarding the performance of Neuro-Patch, like complications and handling, under daily clinical practice when used as intended by the manufacturer

NCT ID: NCT04177914 Recruiting - Hydrocephalus Clinical Trials

HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants

ESTHI
Start date: July 21, 2020
Phase: Phase 3
Study type: Interventional

Hydrocephalus is a potentially debilitating neurological condition that primarily affects babies under a year of age and has traditionally been treated by inserting a shunt between the brain and the abdomen. A newer endoscopic procedure offers hope of shunt- free treatment that may reduce complications over a child's life, but it is not clear if the endoscopic procedure results in similar intellectual outcome as shunt. Therefore, the investigators propose a randomized trial to compare intellectual outcome and brain structural integrity between these two treatments, to help families make the best treatment decision for their baby.

NCT ID: NCT04099823 Recruiting - Alzheimer Disease Clinical Trials

MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics

Start date: October 31, 2019
Phase: N/A
Study type: Interventional

The Researchers are trying to test a MR imaging method for detection of Cerebral Spinal Fluid (CSF) flow in the brain to help diagnosis and better understand diseases that affect brain function.

NCT ID: NCT04011566 Recruiting - Clinical trials for Hydrocephalus, Normal Pressure

Assessment of ShuntCheck Performance Characteristics in Asymptomatic Patients With Normal Pressure Hydrocephalus

Start date: June 11, 2019
Phase:
Study type: Observational

The purpose of the study is to determine if the ShuntCheck test can correctly identify flow or no flow in a ventriculoperitoneal shunt in patients with asymptomatic normal pressure hydrocephalus.