HIV, Clinical Trial
Official title:
Microparticles, Vector of Genetic Information During HIV Infection ?
The aim of the investigators study is to demonstrate in healthy subjects and a cohort of patients infected with HIV, the presence of miRNAs in circulating peripheral blood microparticles (MPs).
| Status | Completed |
| Enrollment | 15 |
| Est. completion date | March 2012 |
| Est. primary completion date | March 2012 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | Male |
| Age group | 30 Years to 50 Years |
| Eligibility |
Inclusion Criteria: - Age of 40 +/-10 years - Seronegativity for the HIV 2 - Patients of the group A: seropositivity for the HIV 1 confirmed in ELISA and Western Blot for at least 2 years and having never received from antiretroviral treatment, with a viral plasmatique load > 1000 copies / ml - Patients of the group B: seropositivity for the HIV 1 confirmed in ELISA and Western Blot for at least 2 years and under stable antiretroviral treatment for at least 6 months, with a viral load undetectable plasmatique (< 40 copies / ml) - patients of the group C : Matching on the age (+/-3 years) to a patient - Be considered healthy by the Investigator after a clinical examination Seronegativity for the HIV 1 confirmed in ELISA the day of the taking Exclusion Criteria: group A et B - Age of < 30 years and > in 50 years - Seropositivity for the HIV 2 group C Seropositivity for the HIV 2 - Be under medicinal treatment |
Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
| Country | Name | City | State |
|---|---|---|---|
| France | Assistance Publique Hopitaux de Marseille | Marseille |
| Lead Sponsor | Collaborator |
|---|---|
| Assistance Publique Hopitaux De Marseille |
France,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | NUMBER OF miRNAs | 2 YEARS | No | |
| Secondary | Demonstrate the presence of miRNAs in microparticles | 2 YEARS | No |