HIV Candidate Vaccine, ALVAC-HIV-1, Administration in HIV-Negative Adults

Status Active, not recruiting

Clinical Trial Summary

The purpose of this study is to determine the best way to administer the candidate HIV vaccine, ALVAC HIV-1 (vCP205).

Clinical Trial Description

Healthy adult volunteers are assigned randomly to either a vaccine or placebo group. Injections are received either intramuscularly, intradermally, or by delivery under the skin of the volunteer's own white blood cells which have had dendritic cell reinfusion. Volunteers are vaccinated at 0, 1, 3, and 6 month time points. Volunteers are closely monitored for 1 hour after vaccination and keep a diary of symptoms for 1 week post-immunization. Volunteers undergo leukopheresis at the start of the study and after the last vaccination at Walter Reed Army Medical Center. Volunteers receive compensation benefits. ;

Study Design

Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00013572
Study type	Interventional
Source	NIH AIDS Clinical Trials Information Service
Contact
Status	Active, not recruiting
Phase	Phase 1

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