HIV Infection Clinical Trial
Official title:
Phase 1b Randomized Double Blind Placebo Controlled Clinical Trial to Evaluate the Safety and Immunogenicity of the Vaccine Regimen ALVAC-HIV (vCP1521) Followed by AIDSVAX® B/E in Healthy, HIV-1 Uninfected Adult Participants in South Africa
The HIV Vaccine Trials Network (HVTN) is doing a study to test 2 experimental HIV vaccines in
combination with 2 licensed vaccines for tetanus and hepatitis B. HIV is the virus that
causes AIDS. Tetanus is an infection that causes muscular spasms. Hepatitis B is a virus that
can cause liver failure.
About 100 people will take part in this study at multiple sites. The US National Institutes
of Health (NIH) is paying for the study.
We are doing this study to answer several questions.
- Are the HIV study vaccines safe to give to people?
- Are people able to take the HIV study vaccines without becoming too uncomfortable?
- How do people's immune systems respond to the HIV study vaccines? (Your immune system
protects you from disease.)
- Can people's immune responses to a tetanus or hepatitis B vaccines help us understand
how their immune systems might respond to the HIV study vaccines?
- Is there a common immune response to licensed vaccines like the tetanus and hepatitis B
vaccines?
n/a
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