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Evaluation of a Simplified Strategy for the Long-term Management of HIV Infection (Simpl'HIV) — Simpl'HIV  

HIV-1-infection Clinical Trial

Official title:
Evaluation of a Simplified Strategy for the Long-term Management of HIV Infection: a Non-inferiority, Randomized, Controlled, Open-label Clinical Trial

Clinical Trial Summary

The purpose of this study is to evaluate whether maintenance antiretroviral therapy could be simplified to DTG + FTC dual therapy and/or patient-centered monitoring once virological suppression is achieved. Using a factorial design, the study aims to assess the efficacy of DTG + FTC dual therapy to maintain virological suppression through 48 weeks of follow-up as well as the costs of a patient-centered ART laboratory monitoring.

Clinical Trial Description

This is a pragmatic multicentre, 2x2 factorial randomized controlled trial with 1:1:1:1 randomization to switching to DTG-based maintenance dual therapy in association with FTC or continuation of cART, and to patient-centered monitoring or continuation of standard monitoring.

Patients will be followed during 48 weeks. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03160105
Study type Interventional
Source University Hospital, Geneva
Contact
Status Completed
Phase Phase 4
Start date May 19, 2017
Completion date May 20, 2019
View Details
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