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Hip Fracture clinical trials

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NCT ID: NCT00655447 Completed - Breast Cancer Clinical Trials

Examining the Long-Term Risks of Oophorectomy

Start date: January 1980
Phase: N/A
Study type: Observational

At the time of hysterectomy for benign disease, the overall health benefits of preserving ovarian function in a large population of women have not been established.

NCT ID: NCT00592813 Completed - Hip Fracture Clinical Trials

Efficacy of a Post-Rehabilitation Exercise Intervention

Start date: April 2008
Phase: N/A
Study type: Interventional

Background: Many people who have suffered a hip fracture are discharged from rehabilitation services with significant residual functional limitations and disability. We believe that a home-based exercise program that incorporates cognitive-behavioral techniques to increase exercise adherence and promote the return to daily activities could extend the benefits of formal rehabilitation for patients who have suffered a hip fracture. Specific Aims: We will conduct a 5-year multi-site randomized controlled trial in patients who have suffered a recent hip fracture and have completed all rehabilitation services. The specific aim that this project will address is whether: Participation in the Strong for Life (SFL) program will improve function and disability outcomes in participants 6-months after they are discharged from rehabilitation services. This study will also investigate the following secondary hypotheses: 1. Changes in function and disability at 6-month follow-up will be correlated with changes in all three proposed intermediary variables: muscle strength, balance, and self-efficacy. 2. The SFL program will significantly improve health-related quality of life among participants at 6-month follow-up. 3. At 9-month follow-up the SFL program will continue to have a significant impact on participants' function and disability compared to the control group. Target population: The target population will be people aged 60 years or more who have suffered a recent traumatic hip fracture, have one or more residual functional limitations and have completed all inpatient, outpatient or homecare rehabilitation services. Intervention: We will use an enhanced version of the Strong for Life program. This home-based exercise program will include both resistance exercises using Thera-bands that will be shown on a video/DVD and weight-bearing exercises that are progressed using a step and/or a weighted vest. A cognitive-behavioral program that is customized for people recovering from hip fracture is being developed that will focus on promoting exercise adherence, decreasing fear of falling and increasing the return to daily activities in the patient's home and community. Design: A randomized controlled clinical trial will be implemented to measure the efficacy of the Strong for Life program. An attention-control intervention will be provided to all participants assigned to the control group. The outcome evaluation points are: - T0: baseline, at the point of discharge from formal rehabilitation; - T2: 6-month outcome assessment - T3: 9-month follow-up Outcomes: The primary outcomes will be function measured by both self-report (AM PAC) and physical performance measures (SPPB). Secondary outcomes include disability, self-efficacy, balance, strength, cognition, and reaction time. Adherence to the exercise program and adverse events will also be monitored.

NCT ID: NCT00582972 Completed - Osteoporosis Clinical Trials

Does Omeprazole Decrease Intestinal Calcium Absorption?

Start date: January 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to measure the effect of omeprazole on intestinal calcium absorption in postmenopausal women.

NCT ID: NCT00523575 Completed - Malnutrition Clinical Trials

Nutritional Intervention in Hip Fracture Patients

Start date: August 2007
Phase: N/A
Study type: Interventional

Hip fractures are highly prevalent and are expected to increase due to the ageing population. Malnutrition is often present in these patients and is associated with prolonged convalescence, lower mobility, lower mental function, lower quality of life and higher complication rate. Nutritional intervention starting soon after hospital admission might reduce complication rate and total length-of-stay by improving nutritional and functional status. Research questions are: 1. Does nutritional intervention reduce total length-of-stay? 2. Is nutritional intervention cost-effective? 3. Can nutritional screening contribute to targeting of nutritional intervention, and thereby reduce costs without loss of effectiveness? Patients randomized to the intervention group will receive oral nutritional supplements (protein and energy enriched) and regular dietetic counselling during hospitalisation and after discharge at patients' homes for 3 months. Patients in the control group will receive usual nurse and dietetic care. Outcome measurements will be taken at baseline, 3 months and 6 months after inclusion.

NCT ID: NCT00424619 Completed - Hip Fracture Clinical Trials

A Randomised, Controlled Comparison of Vitamin D Strategies is Acute Hip Fracture Patients

Start date: October 2007
Phase: Phase 4
Study type: Interventional

The purpose of the study is to determine the best dose of Vitamin D to give to hip fracture patients to achieve the optimal therapeutic level.

NCT ID: NCT00393848 Completed - Osteoarthritis Clinical Trials

Effectiveness of Two Types of Treatment in Restoring Muscle After Hip or Knee Surgery

Start date: October 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the effects of two postoperative interventions designed to preserve muscle protein after major hip or knee surgery.

NCT ID: NCT00390741 Completed - Hip Fracture Clinical Trials

BHS4 - Bone/Muscle Changes Following Hip Fracture in Older White Women

Hip4
Start date: October 1998
Phase: N/A
Study type: Interventional

The major goals of this study are: 1. To conduct an intervention development study to evaluate the feasibility of implementing an exercise intervention for reduction losses in bone mineral density, muscle mass, and strength, and clinically relevant aspects of functioning following a hip fracture, and to obtain preliminary tests of the effective ness of these interventions. 2. To evaluate the effect of home-based exercise intervention on bone metabolism. 3. To evaluate the effects of hip fracture on bone metabolism. 4. To evaluate the effects of exercise and hip fracture on hormonal regulators. 5. To evaluate the association between markers of bone metabolism hormone regulators, and BMD. 6. To separate out the effects of hip fracture on bone turnover from those of aging in persons with low bone mineral density.

NCT ID: NCT00389844 Completed - Hip Fracture Clinical Trials

BHS5 - Testing the Effectiveness of the Exercise Plus Program

Hip5
Start date: July 2000
Phase: N/A
Study type: Interventional

The major goals of this study are: To implement a self-efficacy based intervention to strengthen efficacy beliefs related to exercise, decrease perceived barriers to exercise, and increase exercise behavior and overall activity of older women who have sustained a hip fracture. To test the effectiveness of the Exercise Trainer component of the intervention on exercise behavior, activity, efficacy expectations, barriers to exercise, performance behaviors, overall health status, mood, pain, fear of falling, falls and fall-related injuries at 2, 6, and 12 months following fracture.

NCT ID: NCT00373971 Completed - Hip Fracture Clinical Trials

Preventing Loss of Weight, Fat Free Mass and Activities of Daily Living

Start date: November 1995
Phase: N/A
Study type: Interventional

Malnutrition of elder orthopaedic patients leads to weight loss and loss of fat free mass. Changes in the individual’s nutritional status and body composition may adversely affect the patient’s postoperative level of activity. Aim. Thus, the purpose of the present study is to report changes in postoperative weight, FFM and functions vital to daily living in a group of elder orthopaedic patients that were actively involved in their nutritional care during the hospital stay.

NCT ID: NCT00345969 Completed - Hypogonadism Clinical Trials

Exercise and Testosterone Therapy in Elderly Men With Physical Frailty

Start date: November 2004
Phase: Phase 3
Study type: Interventional

The primary aim of this study is to determine, in hypogonadal older men with physical frailty, whether exercise training combined with testosterone replacement therapy can improve skeletal muscle strength, and lean mass, to a greater degree than exercise training alone.