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Hip Disease clinical trials

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NCT ID: NCT06153940 Recruiting - Hip Disease Clinical Trials

Everglade Stem, World Cup and World Liner Post Market Clinical Follow-up

Start date: November 22, 2023
Phase:
Study type: Observational

The aim of the Study is to monitor the performance of the Signature Orthopaedics Everglade Stem, World Acetabular Cup and World Liner as a part of post-market vigilance and continuous improvement efforts.

NCT ID: NCT06095219 Recruiting - Hip Disease Clinical Trials

MRI-based 3D Hip Labrum and Cartilage Morphology in Patients With Hip Deformities Compared to Asymptomatic Volunteers

Start date: January 18, 2023
Phase:
Study type: Observational

In this study, the investigators seek to describe the normal 3D hip joint morphology in asymptomatic volunteers and compare it to various hip joint deformities. Asymptomatic volunteers will be asked to undergo a non-contrast MRI of the hip at 3 Tesla, utilizing a high-resolution morphologic 3D sequence (3D T2 DESS) that enables the segmentation of labrum and cartilage. 3D morphological parameters of the asymptomatic group will subsequently be compared with the 3D morphological parameters of patients with hip deformities, which were collected as part of a previous retrospective study.

NCT ID: NCT05998720 Recruiting - Hip Disease Clinical Trials

Application of New Magnetic Resonance UTE Technique in Hip Joint Lesions

Start date: July 1, 2023
Phase:
Study type: Observational [Patient Registry]

Explore the imaging and quantitative monitoring of hip bone, cartilage and ligament by magnetic resonance UTE technology, combined with QCT and DXA technology, to provide a more accurate basis for clinical evaluation and treatment.

NCT ID: NCT05465096 Recruiting - Hip Osteoarthritis Clinical Trials

Treatment of Osteoarthritis of the Hip Joint With Intra-articular Injection of Microfractured Autologous Adipose Tissue Containing Mesenchymal Stromal Cells.

Lipo-Hip
Start date: October 24, 2022
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the safety and efficacy up to 12 months of MF-AT in the echo-guided infiltrative treatment of hip OA through clinical, subjective and objective evaluations.

NCT ID: NCT05446623 Recruiting - Hip Arthropathy Clinical Trials

Cardiac Index and General Anesthesia Without Opioid.

OFFLOW
Start date: January 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

General anesthesia used to be based on the association of hypnotics and opioid drugs. But recent studies showed that opioids may be related to a many different complications, like respiratory distress, hyperalgesia. Opioid free anesthesia (OFA) aim is to control de cardiovascular nociceptive response to the surgical stimulation. The scientific literature is not clear yet on the cardiovascular effect of the OFA. Optimization of the cardiac index proved its worth in reducing morbidity and mortality. The purpose of this study is to increase our understanding of the impact of opioid free anesthesia on the cardiovascular system and to evaluate the effectiveness and the security of the technic.

NCT ID: NCT05446181 Recruiting - Hip Fractures Clinical Trials

CLIC1 in Patients Presenting PD

Start date: June 27, 2022
Phase:
Study type: Observational

In this study, mononuclear cells, particularly monocytes, were collected from the peripheral blood of elderly patients who underwent orthopedic hip surgery under spinal anesthesia. We then observe the accumulation of chloride intracellular channel 1 (CLIC1), particularly the characteristic accumulation morphology and its function. The purpose of this study is to compare whether there is a difference in the degree and form of cytoplasmic CLIC1 accumulation between the elderly group with postoperative delirium (PD) and the elderly group without postoperative delirium. We'll also confirm whether this is appropriate as a predictor of postoperative delirium. In addition, we will establish a control group for the non-elderly group to check the difference due to aging itself.

NCT ID: NCT05361980 Recruiting - Pediatric ALL Clinical Trials

Pediatric Orthopaedic Implant Safety & Efficacy

Global POISE
Start date: January 6, 2022
Phase:
Study type: Observational [Patient Registry]

Implant devices are important tools - their use is essential across a number of orthopaedic indications, including hip conditions, trauma and limb deformity. Given the vital role fixation devices play in maintaining alignment, promoting healthy bone healing and preventing joint degeneration, it is essential to understand the expected lifetime outcomes of these implants, and evaluate their safety and efficacy. Prospective implant efficacy and safety registries are needed to support this endeavour, especially considering new regulatory requirements from the European Union Medical Devices Regulation (EU MDR) in relation to post-market clinical follow-up (PMCF).

NCT ID: NCT05199870 Recruiting - Hip Fractures Clinical Trials

MDR - PMCF Study for Echo FX Stem With RingLoc Bipolar Acetabular Cup and Femoral Head

Start date: December 17, 2021
Phase:
Study type: Observational

The objective of this retrospective enrollment and prospective follow-up study is to confirm safety, performance, and clinical benefits of the Echo FX Stem with the RingLoc Bipolar Acetabular Cup and Femoral Head in hip hemiarthroplasty (implants and instrumentation) at a minimum of 10 years follow-up. All available retrospective data will be collected from each patient and a prospective aspect to the study will be necessary to reach the 10-year time point.

NCT ID: NCT04736641 Recruiting - Hip Disease Clinical Trials

Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Japanese Orthopaedic Association Hip Disease Evaluation Questionnaire

Start date: March 1, 2021
Phase:
Study type: Observational

The purpose of this study was to investigate adaptation, validity, and reliability of the Turkish version of the Japanese Orthopaedic Association Hip Disease Evaluation Questionnaire (JOAHDEQ).

NCT ID: NCT04359628 Recruiting - Heart Failure Clinical Trials

How Does Patients' Overall Assessment of Their Health Vary Across and Within Different Disease Groups?

SWEQR
Start date: January 2002
Phase:
Study type: Observational [Patient Registry]

EQ-5D is one of the most commonly employed patient-reported outcome (PRO) measures. It is included in many of the Swedish National Quality Registers (NQRs). EQ-5D health states are usually summarized using 'values' obtained from healthy members of the general public. However an alternative - which remains to be studied in detail - is the potential to use patients' self-reported overall health on the visual analogue scale as a means of capturing experience-based values. The overall aim of this project is to increase knowledge on the potential applicability of EQ VAS as a health state valuation method through assessment of its variability across and within patient groups and compared with that of the general population in Sweden. Data on nearly 700,000 patients from 12 NQRs covering a variety of diseases/conditions and from the general population will be analysed. Longitudinal studies of PROs among different patient groups will be conducted at baseline/first visit and 1-year follow-up. Descriptive analyses comparing EQ-5D health states and observed self-assessed EQ VAS within and across registers will be performed. Comparisons of the change in health state and observed EQ VAS values over one year will also be made. Regression models will be used to assess whether EQ-5D dimensions predict observed EQ VAS values to investigate patient value sets in each NQR. These will be compared across the patient groups and with the existing Swedish experience-based VAS and time trade-off (TTO) value sets obtained from the general population. This research project will provide information on the variation among different patient groups in terms of self-reported health status through EQ VAS and comparison with the general population. Knowledge on the relative importance of different dimensions of the EQ-5D to different patient groups as well as the general population will be gained in this project. The possibility of getting value sets based on patients' self-reported EQ VAS values and their comparison with value sets from experience-based general population studies will be discussed.