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Clinical Trial Summary

This is an open label Phase 2, 2-stage, 2-cohort study to evaluate rucaparib in combination with nivolumab in patients with high-grade serous or endometroid ovarian cancer. Patients entering the following cohorts must have BRCA mutational status confirmed by a central lab: - Cohort A1: No BRCA mutation in tumor; high level of LOH (loss of heterozygosity) - Cohort A2: BRCA mutation in tumor


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03824704
Study type Interventional
Source zr Pharma & GmbH
Contact
Status Terminated
Phase Phase 2
Start date August 23, 2019
Completion date August 24, 2020

See also
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