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Clinical Trial Summary

Phase 2, open-label study of nab-sirolimus in patients with recurrent high grade glioma following prior therapy and patients with newly diagnosed glioblastoma. nab-Sirolimus was administered as single agent or in combination therapies.


Clinical Trial Description

A phase 2, open-label study of nab-sirolimus (also known as ABI-009, nab-rapamycin, albumin-bound rapamycin) in patients with recurrent high grade glioma following prior therapy and patients with newly diagnosed glioblastoma. nab-Sirolimus was administered as single agent or in combination therapies, including temozolomide, bevacizumab, lomustine, and marizomib. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03463265
Study type Interventional
Source Aadi Bioscience, Inc.
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Status Completed
Phase Phase 2
Start date August 1, 2018
Completion date August 26, 2022