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Hernia clinical trials

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NCT ID: NCT01132209 Completed - Pain Clinical Trials

Suture Techniques to Reduce the Incidence of The inCisional Hernia

STITCH
Start date: October 2009
Phase: N/A
Study type: Interventional

The objective of the study is reduction of the incidence of the most frequent complication of abdominal surgery, incisional hernia. In this multi center double-blinded prospective randomized controlled trial, in which a new suture technique using small bites is compared with the traditionally applied large bites (mass closure) technique for midline incisions.

NCT ID: NCT01117337 Completed - Inguinal Hernia Clinical Trials

Comparing Non-fixation of Mesh to Mesh Fixation in Laparoscopic Inguinal Hernia Repair

Start date: September 2008
Phase: Phase 4
Study type: Interventional

The purpose of the study is 1. To compare the recurrence rate of the laparoscopic total extra peritoneal inguinal hernia repair without fixation of the mesh to mesh fixation under spinal anesthesia 2. To test whether non-fixation of mesh leads to less pain compared to the repair when the mesh is fixed.

NCT ID: NCT01115400 Completed - Hernia Clinical Trials

Quality of Life Evaluations in Patients With Abdominal Wall Hernias

QOL
Start date: July 2007
Phase:
Study type: Observational

The aim of this study is to evaluate the quality of life in patients with abdominal wall hernias using a user-friendly survey that is designed specifically for this population of patients. The investigators would like to use this survey to elucidate how quality of life of the patient is changed with the presence of an abdominal wall hernia.

NCT ID: NCT01109771 Completed - Ventral Hernia Clinical Trials

Absorbable Versus Permanent Mesh Fixation Trial in Laparoscopic Midline Ventral Hernia Repair

SORBET
Start date: April 2010
Phase: Phase 4
Study type: Interventional

To compare the use of absorbable tackers versus permanent tack fixation using a polyester large pore mesh in laparoscopic midline ventral hernia repair in a multicenter (Belgian) prospective randomized single-blinded trial. All patients referred for elective midline ventral hernia repair should be assessed for eligibility and entered in a study log, detailing all included patients during the study period.

NCT ID: NCT01105039 Completed - Inguinal Hernia Clinical Trials

Detailed Pain Pattern After Laparoscopic Inguinal Hernia Repair

Start date: November 2009
Phase: N/A
Study type: Observational

Pain after laparoscopic groin hernia repair consist of different pain components (overall pain, shoulder pain, incisional pain and visceral pain). Thus it is important to find out which of these pain components that is most severe, so intervention can be targeted.

NCT ID: NCT01099033 Completed - Hiatal Hernia Clinical Trials

The Biologic Basis of Hernia Formation

Start date: August 2007
Phase:
Study type: Observational

The study will examine potential biological and genetic mechanisms leading to hiatal and paraesophageal hernia formation in predisposed individuals. It is expected that these patients will have defects in the normal production and maturation of collagen and other connective tissue proteins, thus leading to weakness in the diaphragm that may allow for spontaneous herniation. Comparison of tissue and blood samples from these patients (study group) will be made to those from individuals undergoing lower esophageal surgery who have not developed a concurrent hernia (i.e. esophageal myotomy for achalasia and laparoscopic gastric bypass or laparoscopic adjustable gastric banding for morbid obesity - control group).

NCT ID: NCT01086007 Completed - Sexual Dysfunction Clinical Trials

Pain Related Sexual Dysfunction After Laparoscopic Inguinal Hernia Repair

Start date: February 2010
Phase: N/A
Study type: Observational

Previous studies have reported that about 3 % of patients who have had open inguinal herniorrhaphy had a visceral, ejaculatory-related pain. The investigators want to assess this problem among patients after laparoscopic inguinal hernia repair with(self-administered questionnaire study).

NCT ID: NCT01085500 Completed - Inguinal Hernia Clinical Trials

Mastery Learning Inguinal Hernia Repair

Start date: February 2010
Phase: N/A
Study type: Interventional

Abstract: Minimally invasive techniques are now ubiquitous in the management of surgical disease. Competence in laparoscopy requires specialized training and practice. With the decrease of resident work hours, training programs need to explore and adopt efficient strategies to teach and evaluate laparoscopic skills. For economic, ethical, and legal considerations, the operating room may no longer be the ideal environment for teaching these basic technical skills. There appears to be a role for simulation in response to this need. The transfer of laparoscopic skills learned in a simulated environment to the operating room has showed mixed results. Overall, it seems that surgical skills training outside the operating room is beneficial, but the best method(s) of designing, implementing and evaluating such skills curriculums have yet to be identified. The laparoscopic totally extraperitoneal (TEP) inguinal hernia repair is an example of a procedure that is associated with a steep learning curve and requires mastery of basic laparoscopic skills. In addition, an increased recurrence and complication rates in the early learning curve of this procedure, underscores the importance of adequate training. The current practice of teaching the TEP repair in the operating room under an apprenticeship-based model is associated with increased operative time and costs. We propose that the training of surgical trainees outside the operating room with a structured, mastery oriented simulation-based curriculum will help reduce the learning curve of the TEP repair, improve operative performance, and decrease operative time and costs.

NCT ID: NCT01073072 Completed - Clinical trials for Potentially Contaminated Hernia Repair

Study Comparing Tutomesh® Repair to Conventional Surgical Techniques in Potentially Contaminated Hernia Repair and Abdominal Wall Reconstruction

Tutomesh
Start date: January 2009
Phase: Phase 3
Study type: Interventional

This is a multicentric prospective randomized study comparing technique of tension-free repair with placement of a bovine pericardium bioprosthesis (Tutopatch® and Tutomesh®) to current conventional surgical techniques in potentially contaminated hernia repair and abdominal wall reconstruction. The hypothesis is that using Tutomesh® prostheses reduces the risk of postoperative complications at 30 days in the treatment of incisional hernias or complicated abdominal wall hernias (ref early complications) for potentially contaminated fields.

NCT ID: NCT01060046 Completed - Ventral Hernia Clinical Trials

Analysis and Characterization of Biologic Implants

Start date: August 2007
Phase:
Study type: Observational

The purpose of this study is to investigate what happens to biologic mesh in the body over time on a molecular level. To date, it is not known what agents, enzymes, or proteins are interacting at the implantation site that contributes to mesh remodeling and/or degradation. Investigators on this project will identify patients with previously placed mesh who are needing reoperation on the same site and take a biopsy of the mesh during the normal course of surgery. Basic data surrounding the surgical procedure will be collected. The mesh samples will be analyzed for enzymes and proteins and examined histologically for processes that signify remodeling and/or degradation. Control patients will undergo biopsy of abdominal fascia at laparoscopic trocar sites in a manner that will not affect the outcome(s) of their procedure or other risk to the incision site.