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Hernia clinical trials

View clinical trials related to Hernia.

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NCT ID: NCT06040723 Completed - Clinical trials for Gastroesophageal Hernia

Hill-grade Knowledge Via Integrated Neural-network for Gastroscopy

HillKING
Start date: October 10, 2023
Phase:
Study type: Observational

The Hill classification, also known as the Hill grade, is a system used to classify the severity of gastroesophageal valve incompetence, specifically related to gastroesophageal reflux disease (GERD) and hiatal hernia. This study aims to compare the ability of physicians versus an AI model to asses the Hill grade during gastroscopy.

NCT ID: NCT06039800 Recruiting - Hernia Clinical Trials

Patient-reported Outcomes for Patients Undergoing Surgery at Shouldice Hospital.

PROM project
Start date: August 1, 2023
Phase:
Study type: Observational

Background: Previous publications have highlighted limited data on patient outcomes and experiences at Shouldice Hospital. Existing studies from Europe reported outcomes following Shouldice repair but lacked recent data. The current project seeks to optimize patient care and knowledge through systematic follow-up. Study Objectives: Establish a patient-reported outcome measure follow-up program. Evaluate postoperative complication rates. Determine important outcomes to patients. Establish and monitor patient satisfaction with decision-making and hernia repair. Hypotheses/Research Questions: Several research questions related to patient motivations, outcomes, knowledge, and satisfaction are posed for investigation. Potential Risks and Benefits: No anticipated risks to participants. Participants won't directly benefit but contribute to improving patient care and knowledge. Study Design: The study employs a prospective follow-up approach. Surveys are sent at specific intervals (30-40 days, 1-year, 3-years, and 5-years) via email. Consent forms are included in the email, allowing participants to choose their level of involvement. Data is collected from survey responses, patient charts, and operative notes. Study Population: All patients aged 16-90 who underwent hernia surgery at Shouldice Hospital are eligible. Exclusion criteria: Lack of an email address. The required sample size is unknown, and this study serves as a pilot. Data Collection: Data is collected from surveys, patient charts, and operative notes. Consent is obtained through deferred consent (initial contact via email, with consent forms provided). Safeguards are in place to protect personal health information. Duration of Study: Estimated to take 5-6 years. Recruitment/enrollment: 6-12 months. Follow-up: 5 years from the last enrolled participant. Data analysis and write-up: 5 months. Overlap with Other Projects: Concerns about overlap with other studies are addressed, and concurrent participation is allowed. Participants can withdraw at any time. In summary, this research project aims to gather comprehensive data on hernia surgery outcomes, patient experiences, and satisfaction at Shouldice Hospital through a systematic follow-up approach, contributing to the improvement of patient care and knowledge in this field.

NCT ID: NCT06034652 Completed - Hernia Clinical Trials

T-GENVIH-003 LTFU (Long Term Follow Up) Study

Start date: September 12, 2023
Phase:
Study type: Observational

The T-GENVIH-003 study will collect additional, longer term performance data of Gentrix® Surgical Matrix used for reinforcement of ventral hernia repairs from a subset population (i.e., the twenty-one minimally invasive surgical approach cases) from the prior T-GENVIH-002 study.

NCT ID: NCT06032910 Recruiting - Bladder Cancer Clinical Trials

Surgical Mesh in Radical Cystectomy to Prevent Parastomal Hernias

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

Radical cystectomy with ileal conduit urinary diversion serves as a foundational curative treatment strategy for selected patients afflicted with urothelial carcinoma of the bladder. Parastomal hernia after this procedure is an underestimated and undertreated clinical entity, which heavily impairs patients' quality of life due to symptoms of pain, leakage, application or skin problems. There is little evidence about prophylactic mesh placement for parastomal hernia prevention. In this study we examine the use of meshes during radical cystectomy and compare them with a control group.

NCT ID: NCT06024460 Recruiting - Clinical trials for Lumbar Disc Herniation

Non-pharmacological Treatment vs Pharmacological Treatment for Non-acute Lumbar Disc Herniation

Start date: June 9, 2023
Phase: N/A
Study type: Interventional

This is a randomized controlled study comparing non-pharmacological treatment to proactive pharmacological treatment for patient with non-acute lumbar disc herniation with moderate or higher levels of pain. The study involves 200 adult patients aged 19-69, with 50 patients from each participating hospital. Patients will be randomly assigned to either the non-pharmacological treatment group or the pharmacological treatment group 1:1 ratio. Specific interventions will be determined by doctors and Korean medicine doctors without predefined treatment strategies. The non-pharmacological treatment include acupuncture, electroacupuncture, spinal manual therapy and motion style acupuncture. The pharmacological treatment include medication prescription, injection, and nerve block. Treatment period is 8 weeks, and f/u for 3 years.

NCT ID: NCT06023719 Recruiting - Disc Herniation Clinical Trials

Safety And Performance Of Disc Care To Prevent Lumbar Disc Herniation Recurrence

ACE-2
Start date: November 2023
Phase: N/A
Study type: Interventional

The goal of this clinical investigation is to learn about DISC Care, an Hernia Blocking System, in patients who have undergone lumbar disc hernia surgery. The main questions it aims to answer are: - if the implant (DISC Care) prevents disc herniation recurrence - if DISC Care is a safe device Participants will be implanted with DISC Care and followed up for two years (7 visits).

NCT ID: NCT06023394 Recruiting - Inguinal Hernia Clinical Trials

Laryngeal Mask Airway in Laparoscopic Hernia Repair

Start date: March 27, 2023
Phase: N/A
Study type: Interventional

This prospective randomized study will evaluate the effectiveness of laryngeal mask airway (LMA) versus endotracheal intubation (ETT) for patients undergoing laparoscopic inguinal hernia at CMH.

NCT ID: NCT06022263 Recruiting - Clinical trials for Lumbar Disc Herniation

STA363 in the Treatment of Lumbar Disc Herniation

Start date: July 25, 2023
Phase: Phase 1
Study type: Interventional

The goal of this clinical trial is to establish safety and tolerability of STA363 injected into a herniated intervertebral disc in patients with sciatica due to disc herniation. The main questions the trial aims to answer are: 1. Is the treatment safe and tolerable? 2. Does the volume of the disc and the herniation decrease? 3. Is sciatica reduced? Participants will be given an injection into the herniated disc of either placebo or STA363 (one dose). Researchers will compare safety, tolerability, effects on disc and herniation volume and on symptoms between the group of patients injected with placebo and the group injected with STA363.

NCT ID: NCT06016426 Recruiting - Ventral Hernia Clinical Trials

Mass Closure vs Layer by Layer Closure

Start date: September 30, 2023
Phase: N/A
Study type: Interventional

to assess two different ways of closure of laparotomy in children and infants

NCT ID: NCT06014749 Recruiting - Regional Anesthesia Clinical Trials

Serratus Intercostal Block Versus Epidural Analgesia in Eventration: Prospective Observational Study

Start date: September 1, 2022
Phase:
Study type: Observational [Patient Registry]

Adequate pain control, rehabilitation and early postoperative recovery are currently the model to follow according to the recommended guidelines.In this project the main objective is to evaluate 2 different analgesic strategies both intraoperatively and postoperatively, one based on 1. Epidural analgesia and the other 2. Echoguided serratus intercostal block prior to surgical intervention in eventration or abdominal wall repair interventions. We conducted an observational study with a low level of intervention. Epidural analgesia prior to general anesthesia and serratus-intercostal block prior to general anesthesia) following the criteria applied in each case according to the operating room anesthesiologist until reaching the sample size and fulfilling the criteria of: abdominal eventration repair, over 18 years of age, ASA I-III. Signature of the IC.